Synthetic analogs of a molecule extracted from Piper malacophyllum displayed up to 40 times the potency of standard drugs used against the protozoans that cause Chagas disease and visceral leishmaniasis.
Article by Brazilian researchers in The Journal of Clinical Pharmacology finds benefits of new therapeutic scheme to be equivalent to daily dose, with a lower risk of gastrointestinal complications.
The new species are dogfishes belonging to the genus Squalus. They are roughly 70 cm long and weigh about 4 kg. Their habitat begins where the continental shelf ends and extends into the abyssal depths of the ocean.
Researchers deploy mass spectrometry imaging to identify and quantify compounds present in drugs, cosmetics and foods quickly, cheaply and without toxic waste.
International consortium of public health research agencies supports research on chronic non-communicable diseases. FAPESP has also joined GloPID-R, a global research network that focuses on infectious diseases.
Startup supported by FAPESP develops novel acoustic fingerprinting platform that counts number of times songs are played by radio stations, TV channels and Internet users.
Researchers detect mcr-1 in bacteria isolated from food animals and report the first case of human infection in Brazil by a colistin-resistant strain of E. coli also harboring the gene.
US trials prove efficacy of three formulations developed by team including São Paulo-based scientists affiliated with FAPESP-funded Zika Research Network.
Although Latin American countries and BRICS nations are the largest users of nitrogen fertilizer, the impacts of reactive nitrogen emissions have not been evaluated.
Produced by the Center for Metropolitan Studies, the book sets out to make data for São Paulo comparable with data for other major cities of the 'South' and to help reformulate urban theories.
Paper published in Infection and Immunity shows that stimulating production of cytokine IL-17A in infected organism helps reduce parasite load and prevents lesions in organs.
Dominant females of orchid bee species encourage unrelated subordinates to stay in the nest and cooperate but exert reproductive control over related subordinates.
In search of new treatments for diabetes, researchers at the University of Campinas in Brazil investigated the effect of valproic acid and trichostatin on cells grown in the laboratory.
Researchers at UNIFESP evaluated the extent to which several types of physical activity, including deep-water running, swimming and walking, alleviated pain and improved quality of life for patients with fibromyalgia
Paulo Artaxo, a physics professor at the University of São Paulo, acted as science advisor to the team who produced the climate change video shown during the Rio Olympics opening ceremony
Experiment performed at University of São Paulo's Food Research Center with 60 animals and explores a little-known influence of paternal diet on daughters' health
Brazilian study suggests that bacterial components may activate innate immune system receptors and contribute to the development of adaptive response to insulin-producing beta cells
Study focused on Tithonia diversifolia, known to have anti-inflammatory and anti-microbial properties, among others, and established a model for management of several species
Results of in vitro experiments published in Oncotarget show that inhibition of a non-coding RNA named RMEL3 can reduce tumor cell proliferation and viability by up to 95%.
While not reducing weight gain in experiments with rats, resistance training prevented increases in blood pressure and other metabolic damage caused by unhealthy eating habits.
Complete inventory of more than 35,000 species of bacteria and fungi in sugarcane has been published in Scientific Reports with a new method for studying their functions.
Researchers in the University of Texas at Austin and the University of São Paulo have found that Miconia affinis maintains high genetic diversity and flow between forest fragments
Researchers conduct world's first scientific investigation of light-emitting beetle larvae in clay caves in Pará State, Brazil, and report occurrence of luminous termite mounds in the Amazon.
Aerobic exercise reduces or reverses the inflammation caused by asthma, slows the progression of chronic obstructive pulmonary disease, and protects against infections.
The study, in which a Brazilian PhD student took part, involved an experimental calculation of the interaction constant between atoms, confirming the theoretical value.
Study suggests control of emissions from unregulated and underestimated sources such as wood-fired pizza ovens and barbecues would improve air quality in metropolitan area.
Study by Brazilian and US researchers published in The New England Journal of Medicine evidences the possibility of inducing synthesis of telomerase, the "cellular elixir of youth".
Researchers affiliated with Mackenzie Presbyterian University, in collaboration with colleagues in Brazil and elsewhere, are the first to observe solar flares at 3 THz and 7 THz.