News

In pre-clinical tests conducted at the University of São Paulo, compounds called batzelladins were effective even against strains of Plasmodium that are resistant to conventional antimalarial drugs.

Called BR4, the microorganism breaks down PET and produces PHB, a high-quality biopolymer that can be used to manufacture sustainable packaging and for biomedical applications.

In a review article, researchers highlight the challenges that must be overcome to increase the performance and lifetime of MS-SOFC fuel cells while reducing the cost and environmental impact.

The study compared theoretical predictions with data from particle collisions carried out at the LHC and RHIC. Maldacena’s conjecture showed strong convergence with the experimental results.

According to a study conducted by researchers in the state of São Paulo, Brazil, more deforested areas have fewer species that are more similar to each other and perform the same ecological functions. The authors say this phenomenon compromises the resilience of the ecosystem.

Based on the analysis of the genotypes of 500 volunteers, the research project aims to develop a panel of prognostic biomarkers and differentiate Alzheimer’s disease from other types of dementia using blood tests.

A study by Brazilian scientists shows that a by-product of industrial sunflower oil extraction can be used to produce functional breads with high nutritional value.

In tests with rodents, researchers from the State University of Campinas and their collaborators found that hyperactivation of the PARP1 protein after exhaustive training was associated with decreased performance, fatigue, and behavioral symptoms of overtraining. Animals treated with a drug that inhibits the molecule’s activity did not exhibit the condition.

A pilot intervention project involving playful activities that engaged motor skills and cognition showed promising results in improving eye movements and reading speed in eleven children with dyslexia.

FAPESP will begin supporting the Latin American Center for Medical Mycology, a global network of laboratories led by the University of Exeter in the United Kingdom, which also has a unit in South Africa and will soon open another in Asia. Over five years, the foundation will contribute approximately £ 750,000, while the British institution will invest an additional £ 1 million.

A project in the Chico Mendes Extractive Reserve shows that rubber provides adequate income to sustain livelihoods and conserve the forest. However, nut collection yields low pay, which contributes to the adoption of unsustainable practices such as extensive cattle ranching.

Acetic acid, a component of vinegar, was used by researchers in the state of São Paulo to fractionate kraft lignin. The method produces nanoparticles with different properties, including UV protection.

Unprecedented experiment reproduces phase transition in system with short-range interactions, challenging traditional predictions of physics.

Researchers at a FAPESP-supported research center have combined innovative techniques to determine the chromosome number of species of the genus Vellozia, typical of this montane savannah ecoregion. The result provides support for conservation programs and biotechnological applications.

A yeast experiment conducted at a FAPESP-supported research center shows how deficiencies in the proteasome, which is responsible for eliminating damaged and non-functional proteins, affect the metabolism of mitochondria, the organelles that generate energy for cells.

An experiment conducted at the State University of Campinas showed that FGF19, produced in the intestine, acts on specific regions of the brain, causing the body to burn energy to produce heat; the discovery paves the way for new drugs.

By analyzing patient samples, Brazilian researchers identified the species Fusobacterium nucleatum in nearly 60% of cases, with a higher prevalence in oropharyngeal tumors. This microorganism has also been associated with the development of colorectal cancer.

Findings published in the International Journal of Biological Macromolecules could guide studies aimed at treating diseases such as osteoporosis.

Blood and urine analyses of the population living in the Mundaú lagoon complex revealed a greater presence of chemical contaminants and metabolic alterations that can exacerbate chronic diseases, such as diabetes and hypertension. These results underscore the need to monitor the health of the inhabitants and control the sources of contamination.

Sodium and tungsten bronze nanorods have various applications, including use in devices capable of controlling indoor lighting and climate control.

The ingredient, extracted from the plant’s seeds, is a good source of protein and has a neutral flavor and aroma, making it easy to use in food products.

An experiment carried out by researchers from São Paulo State University on zucchini crops indicated that a 30% drop in rainfall would reduce the availability of calories in the sweet liquid that serves as food for pollinators, such as bees, by 34%, while extreme drought practically wipes out the resource. These results are particularly concerning for plants that depend on cross-pollination.

In animal tests, the molecule developed in South America has been shown to prevent fat accumulation and treat existing obesity and associated metabolic disorders. Initial human studies have confirmed the safety of the compound.

The assessment was made by Barbara Pompili, the French Ambassador for the Environment, at the opening of a forum at the National Museum of Natural History in Paris. The event is part of the FAPESP Week France program.

The goal of reintroducing the bird is to restore the original fauna of the forest and its functionality. Supported by FAPESP, the project was presented at the Brazil-France Forum on Forests, Biodiversity, and Human Societies in Paris.

At a symposium in Paris, a University of São Paulo professor of zoology explains how new technologies allow for the use of degraded DNA from specimens preserved for decades, contributing to the advancement of scientific knowledge and the conservation of biodiversity.

Researchers, institution leaders, and representatives of indigenous communities discuss the importance of natural history museums and their role in the 21st century at a symposium during FAPESP Week France.

In partnership with FAPESP, the National Museum of Natural History of France is holding a seminar for scientists, museologists, and representatives of indigenous communities to discuss new visions and missions for these institutions.

Researchers from Brazil and France meet at a seminar during FAPESP Week to discuss ways forward for museums in the face of the changes and challenges of the 21st century.

During the visit, a cooperation agreement was signed between the University of São Paulo and the National Museum of Natural History.

The study compared data from patients and healthy individuals from Brazil, Canada, and the United States. The results help paint a clearer picture of how genetics influences the development of OCD.

At the 4th FAPESP 2025 Conference, the former vice chair of the IPCC stated that the renewable energy sector is growing faster than the fossil fuel sector. She said she has not lost hope that the global average temperature increase can be limited to 1.5 °C above pre-industrial levels.

Researchers from the University of São Paulo have identified a molecule in arachnid venom that acts similarly to a commonly used chemotherapy drug for treating the disease; preliminary results of the study were presented at FAPESP Week France.

At VivaTech in Paris, research center coordinators showcase the advances made at the University of São Paulo in agriculture, climate, energy, computing, artificial intelligence, and health.

Scientists from the Curie Institute and the University of São Paulo are about to conduct a clinical study to evaluate the safety and efficacy of a new CAR-T cell-based immunotherapy for patients with oculocerebral lymphoma; the project was presented at FAPESP Week in Toulouse.

University of São Paulo researchers are developing an aircraft equipped with sensors that can detect and measure the concentrations of carbon dioxide and methane in the environment; the project was presented at FAPESP Week France in Toulouse.

Delegation visiting France to participate in FAPESP Week learns about the instruments available at the French National Center for Scientific Research to support innovation and startups.

Research by the Center for the Development of Functional Materials and the State University of Campinas addresses an important process for generating energy and producing high value-added chemical products.

Study shows that carbon and nitrogen losses from the soil persist for nearly a decade after burning, and conversion to agriculture causes even more severe impacts.

By combining different techniques, researchers at São Paulo State University in Brazil have revealed biological pathways related to tenderness, fat deposition, and other relevant characteristics of the meat of the predominant cattle breed in Brazil. The results could optimize strategies to enhance product quality and bolster the competitiveness of Brazilian livestock farming.

Researchers have found a substance in propolis from bees native to Brazil that kills 90% to 100% of Aedes aegypti larvae. The compound, found in pine sap, is likely enhanced by insect processing and has the potential to help combat mosquitoes that transmit arboviruses.

The evaluation of predictive models for low birth weight cases was based on data from a population study of over 1,500 pregnant women in the city of Araraquara in the state of São Paulo, Brazil. Early identification of the problem is crucial for effective intervention.

Over the course of three years, researchers from the University of São Paulo and their collaborators examined the “belief in a just world” of 659 São Paulo residents between the ages of 12 and 14. The results highlight the importance of incorporating urban and structural factors, such as access to services and community cohesion, into discussions on citizenship and democratic development.

With support from USP and FAPESP, scientists and entrepreneurs showcase their innovative research in areas such as agriculture, climate, photonics, artificial intelligence, materials, and health in Paris.

The assessment was made by participants in the opening session of FAPESP Week France in Toulouse.

At Europe’s largest innovation event, Jensen Huang, CEO of NVIDIA, describes a scenario in which factories, robots, and industrial systems will be developed and tested digitally before going into operation.

The aircraft’s design is inspired by albatrosses, which exploit atmospheric turbulence to fly for long periods with minimal effort and energy expenditure; the project, developed by French engineers, was presented during FAPESP Week France.

With support from FAPESP, the São Paulo startup has developed a molecule that can stimulate the immune system to fight cancer caused by the human papillomavirus; the technology will be presented at the VivaTech fair in Paris.

The system, developed by the FAPESP-supported startup, performs an assessment in eight minutes, drastically reducing the time needed to save lives; the technology will be presented at VivaTech in Paris.

The Campinas-based startup has developed its own biofabrication and tissue engineering technologies with support from FAPESP; these solutions will be presented at Europe’s largest innovation fair in Paris.