In tests with rodents, researchers from the State University of Campinas and their collaborators found that hyperactivation of the PARP1 protein after exhaustive training was associated with decreased performance, fatigue, and behavioral symptoms of overtraining. Animals treated with a drug that inhibits the molecule’s activity did not exhibit the condition.
In animal tests, the molecule developed in South America has been shown to prevent fat accumulation and treat existing obesity and associated metabolic disorders. Initial human studies have confirmed the safety of the compound.
The assessment was made by Barbara Pompili, the French Ambassador for the Environment, at the opening of a forum at the National Museum of Natural History in Paris. The event is part of the FAPESP Week France program.
A study by Brazilian scientists shows that a by-product of industrial sunflower oil extraction can be used to produce functional breads with high nutritional value.
FAPESP will begin supporting the Latin American Center for Medical Mycology, a global network of laboratories led by the University of Exeter in the United Kingdom, which also has a unit in South Africa and will soon open another in Asia. Over five years, the foundation will contribute approximately £ 750,000, while the British institution will invest an additional £ 1 million.
Researchers at a FAPESP-supported research center have combined innovative techniques to determine the chromosome number of species of the genus Vellozia, typical of this montane savannah ecoregion. The result provides support for conservation programs and biotechnological applications.
A project in the Chico Mendes Extractive Reserve shows that rubber provides adequate income to sustain livelihoods and conserve the forest. However, nut collection yields low pay, which contributes to the adoption of unsustainable practices such as extensive cattle ranching.
Acetic acid, a component of vinegar, was used by researchers in the state of São Paulo to fractionate kraft lignin. The method produces nanoparticles with different properties, including UV protection.
A pilot intervention project involving playful activities that engaged motor skills and cognition showed promising results in improving eye movements and reading speed in eleven children with dyslexia.
Unprecedented experiment reproduces phase transition in system with short-range interactions, challenging traditional predictions of physics.
A yeast experiment conducted at a FAPESP-supported research center shows how deficiencies in the proteasome, which is responsible for eliminating damaged and non-functional proteins, affect the metabolism of mitochondria, the organelles that generate energy for cells.
The Campinas-based startup has developed its own biofabrication and tissue engineering technologies with support from FAPESP.
The Campinas-based startup has developed its own biofabrication and tissue engineering technologies with support from FAPESP.