Cancer
2025-07-15
AI-based tool can ‘measure’ cancer aggressiveness and paves the way for new therapies
Developed at the University of São Paulo, the model uses protein expression to create a stemness index that analyzes the similarity of tumors to pluripotent stem cells. The article was published in Cell Genomics.
Biomedicine
2025-07-08
Group is investigating biomarkers for the early detection of Alzheimer’s disease
Based on the analysis of the genotypes of 500 volunteers, the research project aims to develop a panel of prognostic biomarkers and differentiate Alzheimer’s disease from other types of dementia using blood tests.
Health
2025-07-02
Overtraining: the cause of symptoms caused by excessive physical exercise has been discovered
In tests with rodents, researchers from the State University of Campinas and their collaborators found that hyperactivation of the PARP1 protein after exhaustive training was associated with decreased performance, fatigue, and behavioral symptoms of overtraining. Animals treated with a drug that inhibits the molecule’s activity did not exhibit the condition.
Innovation
2025-07-16
Researchers obtain patent for formula that induces germination and accelerates plant growth
The solution is produced using chalcone, a chemical substance from the flavonoid family, and has the potential to be used in agriculture and forest restoration.
FAPESP Conferences 2025
2025-07-16
‘Africa needs to be recognized as a producer of knowledge and interpretations of the world’
Eurídice Monteiro, the former Secretary of Higher Education in Cape Verde, delivered the 5th FAPESP 2025 Conference. She argued that science is a tool for liberation, grounded in African contributions, cognitive justice, and South-South integration.
Conservation
2025-07-16
Historical and current population DNA reveals that there are at least 12 species of rocket frogs, three of which are already extinct
Researchers at the University of São Paulo extracted genetic material from animals kept in museums for a hundred years and from others living in the wild and concluded that they are a new genus with at least a dozen species. The group is working quickly to identify them all and direct conservation efforts in the Atlantic Forest, where they live.
Functional materials
2025-07-16
Electrochemical route allows for the synthesis of giant fullerenes at a lower cost and with less environmental impact
Researchers at the University of São Paulo and Sapienza Università di Roma obtained the material without the need for high temperatures. The product has many potential applications, ranging from electronics to cosmetics.
Aging
2025-07-16
Researchers at the University of São Paulo create more complex mini-brains to study the key to healthy aging
Organoids were developed from the blood cells of centenarians who are part of a project conducted at the Human Genome and Stem Cell Research Center to discover genes that protect the brain from the effects of aging.
Evolution
2025-07-15
Reduction in supply of prey was decisive factor in extinction of saber-toothed tigers, study finds
Cross-referencing climate data and fossils from around 15 million years ago shows that the decline in prey availability may have played a role in the extinction of these felines. Another study cites competition with elephants and an increase in predators as factors that reduced the once diverse antilocaprids to a single species today.
Natural products
2025-07-09
Substances isolated from marine sponges show potential for treating malaria
In pre-clinical tests conducted at the University of São Paulo, compounds called batzelladins were effective even against strains of Plasmodium that are resistant to conventional antimalarial drugs.
Atlantic Forest
2025-07-09
Forest cover and type of environment shape functional diversity of insectivorous birds in the Atlantic Forest
According to a study conducted by researchers in the state of São Paulo, Brazil, more deforested areas have fewer species that are more similar to each other and perform the same ecological functions. The authors say this phenomenon compromises the resilience of the ecosystem.
FAPESP Conferences 2025
2025-07-16
‘Africa needs to be recognized as a producer of knowledge and interpretations of the world’
Functional materials
2025-07-16
Electrochemical route allows for the synthesis of giant fullerenes at a lower cost and with less environmental impact
Physics
2025-07-09
Holographic correspondence confirms the properties of quark-gluon plasma
Biotechnology
2025-07-09
Brazilian researchers identify bacteria that can transform plastic waste into bioplastics
Natural products
2025-07-09
Substances isolated from marine sponges show potential for treating malaria
Biomedicine
2025-07-08
