Discovery increased the number of known variations of the HER2 protein, the target of advanced drugs against the disease, from 13 to 90; diversity may explain resistance to therapies.
A flying relative of dinosaurs, Bakiribu waridza (“comb mouth” in the Kariri language) filtered crustaceans and other small organisms from rivers and lakes, where it was likely swallowed by a predator that regurgitated it in the Araripe Basin in northeastern Brazil.
The multicenter Titan Trial project is investigating a method to treat unilateral spatial neglect, a sequela of stroke that affects perception of the side opposite to the affected cerebral hemisphere.
A study by the Federal University of São Carlos and University College London examined 2,815 older adults and identified an indicator of loss of mobility.
The chemical compound is used in various industrial processes, but its synthesis is highly polluting. Research involving scientists from the Center for Development of Functional Materials and the Center for Innovation on New Energies, supported by FAPESP, indicates clean ways of obtaining the input.
Brazilian research shows that stellate pancreatic cells produce periostin, remodeling tissue and facilitating tumor infiltration, a key mechanism of the aggressiveness and high mortality of the disease.
Preliminary data suggest that the population in this area of southwestern Pará state is more exposed to infection than average due to a lack of access to healthcare and greater contact with sex workers.
An experiment conducted at the Federal University of São Carlos demonstrated that applying low-intensity light had a hypotensive effect on rats that became hypertensive due to a reduction in hormones, a process characteristic of aging in the female reproductive system.
Batrachochytrium dendrobatidis is responsible for the decline of toad and frog populations across the globe. The origin of the fungal strain was the subject of a study led by researchers at the State University of Campinas.
Researchers compared the repertoire of long non-coding RNAs in humans with those of rhesus monkeys, mice, and chickens and noted that these structures played a role in functional specialization throughout evolution.
Films made from these photosensitive semiconductors promise to be the stars of the next generation due to their ability to convert sunlight into electricity. However, the stability of the material under heat and humidity still needs improvement.
Results indicate that the innate immune response remains activated even with immunosuppressant use, paving the way for new therapies to prevent organ rejection.
Nanoparticle-reinforced wrappers can be filled with various formulations of the granular products needed for crops, a versatility that facilitates application by agribusiness.
São Paulo needs to drive the process of gradually replacing fossil fuels with renewable energy sources in Brazil, said Gilberto Jannuzzi at a conference organized by FAPESP to discuss the path forward for the country after COP30.
According to a study by the University of São Paulo, the effects are intensified when the molecule is applied in conjunction with fluoride and xylitol.
Conservation of natural areas should be a major factor in preventing new pandemics, said Felicia Keesing of Bard College during the first day of the FAPESP Interdisciplinary School.
Brazilian technology from Nanox is recognized for its solution to reduce food loss and waste. The Center for Development of Functional Materials is a FAPESP Research, Innovation, and Dissemination Center based at UFSCar.
The parasitic mites were found on juvenile arachnids in the Butantan Institute collection. The larvae of Araneothrombium brasiliensis were collected in Rio de Janeiro. Previously, the genus had only one known species in Costa Rica.
A study of nearly 900 adults indicates that although smoking is still the main risk factor for lung function loss, systemic inflammation and obesity also increase the risk of developing chronic obstructive pulmonary disease.
A study by the Federal University of São Paulo describes how SARS-CoV-2 interacts with the RNA of infected lung cells in an unprecedented way. The results may guide the search for new treatments and vaccines.
The study also assessed the risks of consuming cocoa and cassava grown in Linhares, a municipality in an area affected by the Fundão dam collapse in Minas Gerais, Brazil, ten years ago.
Water accumulated in the tanks of these plants living high up in trees has much higher concentrations of nitrogen, phosphorus, calcium, potassium, magnesium, sulfur, and iron than rainwater. Plants irrigated with this nutrient-rich water produced almost twice as many leaves.
A comprehensive analysis conducted in 2019 detected the accumulation of 13 heavy metals and other toxic substances, advising against consumption due to risks to human health.
After analyzing over 1,400 cases of squamous cell carcinoma of the head and neck, the study found that more aggressive histopathological variants occur at a rate of 4.6%. Previous estimates pointed to a rate of up to 15%.
At the FAPESP Day Uruguay symposium, Pedro Brancalion, a professor at the University of São Paulo, presented the results of a project that aims to leverage the country’s carbon credit market.
A study of more than 5,000 people over 12 years showed that simple measures to assess the two conditions can facilitate the diagnosis of sarcopenic obesity without complex tests, such as MRI and CT scans. This finding expands access to treatment for older adults.
Alternanthera littoralis, also known as Joseph’s Coat, is native to the Brazilian coast and has traditionally been used to combat microbial infections and parasitic diseases.
A startup supported by the Centelha program has developed a solution that combines cutting-edge technology with ease of use, transforming production lines without the need for expensive automation.
A study analyzing discoveries made over the last 20 years found that nearly half of all snails and slugs were described by researchers who did not work in the countries where they were found.
The Center for Favela Studies project was launched in the municipality of Jacareí, São Paulo state, using data from the state system that registers low-income families in social assistance programs.
Analysis of 309 strains collected in eight countries indicates that the genus Escovopsis emerged 56.9 million years ago, but only began interacting with today’s mutualistic ants 38 million years ago, challenging the theory that they all emerged at the same time.
A review of 467 studies also points out that, instead of alleviating feelings of fear and anxiety, weapons increase them, as well as exacerbating controlling behaviors and causing domestic violence.
Researchers at São Paulo State University are investigating how hormonal fluctuations throughout a woman’s life influence the immune system and how physical exercise can mitigate these effects.
The indigenous peoples have created their own educational institutions based on the idea of “educating through research,” promoting autonomy and critical thinking.
Unprecedented footage of jaguar cichlid being preyed upon was captured after heavy rains caused the overflow of freshwater into Sueste Bay, the species’ feeding ground.
A study by a FAPESP-supported research center showed that the surfaces change when an electron beam is applied. The material has potential for applications in semiconductors, antibacterial agents, gas sensors, and more.
Study identifies 167 native species of the Atlantic Forest with bioeconomic applications: 58% in the medical field, 12% in cosmetics, and 5% in the food sector; 78 species (46.7%) have patents registered in 61 countries, only 8% of them in Brazil.
Combining field research data with climate model projections, a study has reconstructed the activity of the Atlantic Meridional Overturning Circulation – one of the main drivers of the Earth’s climate – throughout the Holocene. Projected scenarios for the future are unlike anything seen in the last 6,500 years.
Project developed in the state of São Paulo, Brazil, allows for the highly efficient extraction of aromatic and bioactive compounds, reducing logistics costs and increasing beer quality.