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The synthetic peptide was inspired by ACE2, the protein to which the virus that causes COVID-19 binds to invade human cells. The results point to a route for the development of novel antivirals.

According to an article published in the journal PNAS, different lineages of amoebae and ancestors of plants, algae and animals were already established in the Neoproterozoic period and survived the two glaciations that covered the entire planet.

A study conducted by Brazilian scientists at São Paulo State University involved 242 volunteers aged 40 on average. The results showed an improvement in heart rate control by the autonomic nervous system regardless of the level of physical activity in adulthood.

A GM strain of brewer’s yeast Saccharomyces cerevisiae developed by Brazilian researchers could significantly grow the production of ethanol biofuel. A patent application has been filed with Brazil’s patent office.

Hurricane Maria killed so many Purple-throated caribs, sole pollinator of two species of heliconia, that other birds were able to gain access to the plants, according to an article in New Phytologist, which concludes that species extinction is a far more complex process than is often thought.

The technology was developed at the Research, Innovation, and Dissemination Center for Neuromathematics in collaboration with scientists from Finland.

The experiment of the Center for Development of Functional Materials was described in an article in the journal ChemCatChem.

In an article published in Perspectives in Ecology and Conservation, researchers affiliated with the National Space Research Institute (INPE) and the National Disaster Surveillance and Early Warning Center (CEMADEN) in Brazil discuss CO₂ emission reduction challenges and solutions.

Promising results were obtained by a group at the Brazilian Center for Research on Energy and Materials (CNPEM), working with collaborators elsewhere. They combined inhibition of glutaminase, an enzyme that converts glutamine into nutrients for tumor cells, with inhibition of HuR, a protein that regulates the RNA of glutaminase.

Characterized by high pH and salinity, these water bodies have practically dried up because of rising temperatures, changing rainfall patterns, and wildfires. The findings show how the local microbial community and other factors influence greenhouse gas emissions.

Experiments conducted at the Federal University of the ABC showed that nitrogen-fixing bacteria play a key role in the reproduction of a legume native to Brazil.

The process designed by researchers at São Paulo State University (UNESP) in Brazil and collaborators in Chile and Mexico results in low-cost raw materials and reduced environmental damage.

Residents of the cities of Bauru and Belo Horizonte were challenged to identify the image and song of the main bird species that inhabit these places.

Computer simulations based on the standard model did not account for observational data obtained via telescope, showing that other factors must be taken into consideration when analyzing the process.

Researchers at UNICAMP and other Brazilian universities, as well as 20 companies, are participating in the DUNE experiment. They are responsible for the argon purification and photon detection processes, without which the international mega-project would be impossible.

The conclusion is from a study of 774 vegans conducted by researchers at the University of São Paulo in Brazil. An article reporting its findings is published in JAMA Network Open.

The product, derived from sugarcane, is being developed by Dermbio Biotech, a startup incubated at the State University of Campinas.

Through morphological and molecular analysis of material collected from rivers in Brazil's Northeast region, the researchers are extending their knowledge of the evolutionary history of South American darters in the genus Characidium.

A study conducted at the University of São Paulo in Brazil helps elucidate the impact of high levels of atmospheric carbon dioxide on human health.

A study by the University of São Paulo shows that expansion of cattle ranching to meet growing domestic demand has contributed more than any other driver to the elimination or degradation of the Amazon’s original vegetation, followed by expanding croplands and urbanization.

A study conducted by Brazilian scientists and colleagues in other countries shows that earthquakes, hurricanes, tsunamis and volcanic eruptions increase the risk of extinction for mammals, birds, reptiles and amphibians. The natural events may have synergies with hazards due to human activity.

The 3D model developed by Djúlio Zanin, a PhD candidate at the University of São Paulo supported by FAPESP, won an award at an international rheumatology conference.

Researchers affiliated with the FAPESP Research Program on Global Climate Change met at the State University of Campinas in Brazil to discuss current research priorities in the effort to understand and combat the consequences of the extreme events caused by global warming.

In addition to providing a detailed description of the morphology of hepatic nerves, the study led by Brazilians showed that the increase in blood sugar was activated by a protein called CREB.

Alex Ruane delivered the 7th FAPESP Lecture 2024 on “Climate Change and Food Security”

Researchers at São Paulo State University (UNESP) in Brazil evaluated the effect of three different low-cost training programs on a group of socially vulnerable female volunteers. HIIT combined with muscle strength exercises was the most efficacious in terms of reducing blood pressure and arterial stiffness, the main risk factors for cardiovascular disease.

In PLOS Pathogens, researchers at the University of São Paulo in Brazil report a study based on autopsies of 47 patients who died after being infected by the ancestral strain of SARS-CoV-2. The findings will support clinical decisions on the treatment of critical cases.

A member of the Center for Research on Biodiversity Dynamics and Climate Change, Mauro Galetti uses his experience from his undergraduate studies in biology to his most recent studies in ecology to tell stories in accessible language that inspire readers to fight for the planet.

A report by an international group of researchers including three Brazilians shows that climate change tripled the probability of weather conditions favoring unprecedented wildfires in Canada and multiplied it by a factor of 20 in western Amazonia between March 2023 and February 2024. Global carbon emissions were 16% above average.

The MoU is the first cooperation agreement between NIH and a foreign partner to cover a wide array of research areas.

The researchers are now looking for a molecule that inactivates the protein expressed by the gene as a basis for a drug that could complement existing medications, which are not always effective and can have adverse side-effects.

The solution, developed by a startup supported by FAPESP, enables farmers to forecast water availability for a six-month horizon.

Among the advantages of the novel methodologies is the possibility of using human cells, leading to higher success rates in the transition from preclinical to clinical trials.

Partnerships among departments of the São Paulo State Government, universities and research centers aim to meet society’s needs by developing devices, software and processes that promote assistance, rehabilitation, and better lives for people with disabilities.

Developed by a laboratory associated with the Center for Research in Inflammatory Diseases, “Conflitulus Lattes” – named after the Brazilian system of information on science and technology – helps avoid conflicts of interest in review panels.

A system created by a startup supported by FAPESP evaluates coffee cherry quality with precision on the production line, reducing waste and enhancing yield.

Brazilian researchers investigated the effects of delivery date manipulation to avoid the Carnival holiday. Their findings suggest Brazilian women are giving birth too early, impairing the health of their babies.

Scientists at the University of São Paulo present this conclusion based on a systematic review of the literature in a paper published in the Journal of Cleaner Production.

In the journal Current Microbiology, Brazilian researchers describe how three strains of bacteria in the genus Lactobacillus can benefit human health and meet the needs of the cheese industry.

Richard Glenn’s aim on his first official visit to Brazil was to strengthen the ties of partnership with FAPESP.

The researchers based their findings, published in Molecular Autism, on data for more than 900 children with ASD and experiments with brain organoids derived from blood cells donated by some of the children.

Thirty-two experts affiliated with academic and research institutions in the North, Northeast and Southeast regions of Brazil wrote its 12 chapters.

According to Brazilian researchers, SARS-CoV-2 uses this strategy to manipulate the machinery of the host’s defense cells. The discovery paves the way for the development of novel therapies.

Experiments with mice at the University of São Paulo used cutting-edge techniques to investigate the neural circuits behind aversive behavior and fear memory. The findings are reported in Current Biology.

An article reporting the study is featured on the cover of Nano Letters; the findings can help design next-generation electronic materials for the semiconductor and nanotechnology industry.

The publication by André de Carvalho, a researcher at the Center for Mathematical Sciences Applied to Industry, is suitable for undergraduates, postgraduates, and professionals.

A startup supported by FAPESP has created a solution that promotes development and growth of the roots and aerial part of plants.

Brazilian researchers publish preliminary data showing that the pathogen has undergone mutations making it more aggressive and contributing to resurgence of the disease in Brazil since 2023.

The analysis was conducted by researchers at São Paulo State University (UNESP), showing that when the patients took the drug, the number of times they woke up during the night fell by 25% and the amount of time they remained awake fell 30% on average.

Trials conducted at the State University of Campinas (UNICAMP) confirm that the isolate of Leishmania amazonensis from a 46-year-old patient is resistant to amphotericin B.