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In mice, researchers observed increased intestinal stem cell proliferation and organ regeneration in the post-fasting period. However, depending on the diet and genetic profile, this can increase the risk of tumors.

In a study of 141 patients, researchers at the Federal University of São Paulo and collaborators evaluated different models to predict which patients would benefit from risperidone treatment.

A study conducted at São Paulo State University characterized the properties of a formulation containing chemically modified flaxseed and Brazil nut oils.

Discovery at the Center for Redox Processes in Biomedicine showed positive results in hypertensive rats and therapeutic potential.

Insper is holding an event supported by FAPESP that will explore key areas for sustainable transformation. Register by August 15.

Model considers two DM particles, one stable and one unstable, as well as a vector mediator similar to the photon but with mass, which would promote interaction with ordinary matter particles.

Brazilian researchers develop precision tool that can predict immunotherapy treatment failure, with the potential to personalize therapies and reduce healthcare costs.

The technique uses laser equipment to scan and create three-dimensional images; the algorithm optimizes the cut, seeking to maintain the balance and health of the tree.

The method is part of a series of international studies on the Canephora species published by Brazilians and can be adapted to identify “fake coffees”.

The assessment was made by British researcher James Wilsdon, executive director of the Research on Research Institute, in an interview with Agência FAPESP.

Researchers reanalyzed the skull musculature of coelacanths, a group of fish that has existed for 400 million years, and concluded that many structures had been incorrectly described. The study was published in Science Advances by researchers from the University of São Paulo and the Smithsonian Institution.

During the pandemic, a preference for domestic vaccines or those from countries such as the United States, Germany, and the United Kingdom was observed for the first time. This phenomenon, known in marketing as the country of origin effect, is usually associated with products that require consumer research before purchase or that have a long tradition in certain countries, such as Swiss chocolates. However, it had never been linked to free vaccines.

The platform, developed at the State University of Campinas, uses the small crustacean Parhyale hawaiensis to determine if a substance can damage sperm DNA and affect fertility.

Some of the results of research in areas such as agriculture, health, technological entrepreneurship, and public policy were presented during a seminar at the Foundation.

Film based on algae and nanocellulose created at the Federal University of São Carlos is safe for the environment, reduces nutrient loss, and could replace microplastics in agriculture.

An analysis of data collected over 20 years in the upper stretch of the river shows a 50% loss in economic gains from fishing. Native fish have become smaller and smaller. Conversely, invasive species, which have a lower market value, are becoming more abundant. The phenomenon has been accompanied by a loss of vegetation cover on the riverbanks.

Three promising brain stimulation methods used in medical practice and academic research.

“Negative balance” of biome protection recorded between 2022 and 2024 could jeopardize Brazil’s international goals, warn Brazilian researchers and their international collaborators in the journal Global Change Biology.

Economic activities that depend directly on marine resources account for 2.91% of gross domestic product and 1.07% of employment. However, when the indirect effects of their linkages with other sectors are considered, the impact increases to 4.45% of employment and 6.39% of the country’s GDP.

Eurídice Monteiro, the former Secretary of Higher Education in Cape Verde, delivered the 5th FAPESP 2025 Conference. She argued that science is a tool for liberation, grounded in African contributions, cognitive justice, and South-South integration.

The solution is produced using chalcone, a chemical substance from the flavonoid family, and has the potential to be used in agriculture and forest restoration.

Researchers at the University of São Paulo and Sapienza Università di Roma obtained the material without the need for high temperatures. The product has many potential applications, ranging from electronics to cosmetics.

Researchers at the University of São Paulo extracted genetic material from animals kept in museums for a hundred years and from others living in the wild and concluded that they are a new genus with at least a dozen species. The group is working quickly to identify them all and direct conservation efforts in the Atlantic Forest, where they live.

Organoids were developed from the blood cells of centenarians who are part of a project conducted at the Human Genome and Stem Cell Research Center to discover genes that protect the brain from the effects of aging.

Developed at the University of São Paulo, the model uses protein expression to create a stemness index that analyzes the similarity of tumors to pluripotent stem cells. The article was published in Cell Genomics.

Cross-referencing climate data and fossils from around 15 million years ago shows that the decline in prey availability may have played a role in the extinction of these felines. Another study cites competition with elephants and an increase in predators as factors that reduced the once diverse antilocaprids to a single species today.

In pre-clinical tests conducted at the University of São Paulo, compounds called batzelladins were effective even against strains of Plasmodium that are resistant to conventional antimalarial drugs.

Called BR4, the microorganism breaks down PET and produces PHB, a high-quality biopolymer that can be used to manufacture sustainable packaging and for biomedical applications.

In a review article, researchers highlight the challenges that must be overcome to increase the performance and lifetime of MS-SOFC fuel cells while reducing the cost and environmental impact.

The study compared theoretical predictions with data from particle collisions carried out at the LHC and RHIC. Maldacena’s conjecture showed strong convergence with the experimental results.

According to a study conducted by researchers in the state of São Paulo, Brazil, more deforested areas have fewer species that are more similar to each other and perform the same ecological functions. The authors say this phenomenon compromises the resilience of the ecosystem.

Based on the analysis of the genotypes of 500 volunteers, the research project aims to develop a panel of prognostic biomarkers and differentiate Alzheimer’s disease from other types of dementia using blood tests.

A study by Brazilian scientists shows that a by-product of industrial sunflower oil extraction can be used to produce functional breads with high nutritional value.

In tests with rodents, researchers from the State University of Campinas and their collaborators found that hyperactivation of the PARP1 protein after exhaustive training was associated with decreased performance, fatigue, and behavioral symptoms of overtraining. Animals treated with a drug that inhibits the molecule’s activity did not exhibit the condition.

A pilot intervention project involving playful activities that engaged motor skills and cognition showed promising results in improving eye movements and reading speed in eleven children with dyslexia.

FAPESP will begin supporting the Latin American Center for Medical Mycology, a global network of laboratories led by the University of Exeter in the United Kingdom, which also has a unit in South Africa and will soon open another in Asia. Over five years, the foundation will contribute approximately £ 750,000, while the British institution will invest an additional £ 1 million.

A project in the Chico Mendes Extractive Reserve shows that rubber provides adequate income to sustain livelihoods and conserve the forest. However, nut collection yields low pay, which contributes to the adoption of unsustainable practices such as extensive cattle ranching.

Acetic acid, a component of vinegar, was used by researchers in the state of São Paulo to fractionate kraft lignin. The method produces nanoparticles with different properties, including UV protection.

Unprecedented experiment reproduces phase transition in system with short-range interactions, challenging traditional predictions of physics.

Researchers at a FAPESP-supported research center have combined innovative techniques to determine the chromosome number of species of the genus Vellozia, typical of this montane savannah ecoregion. The result provides support for conservation programs and biotechnological applications.

A yeast experiment conducted at a FAPESP-supported research center shows how deficiencies in the proteasome, which is responsible for eliminating damaged and non-functional proteins, affect the metabolism of mitochondria, the organelles that generate energy for cells.

An experiment conducted at the State University of Campinas showed that FGF19, produced in the intestine, acts on specific regions of the brain, causing the body to burn energy to produce heat; the discovery paves the way for new drugs.

By analyzing patient samples, Brazilian researchers identified the species Fusobacterium nucleatum in nearly 60% of cases, with a higher prevalence in oropharyngeal tumors. This microorganism has also been associated with the development of colorectal cancer.

Findings published in the International Journal of Biological Macromolecules could guide studies aimed at treating diseases such as osteoporosis.

Blood and urine analyses of the population living in the Mundaú lagoon complex revealed a greater presence of chemical contaminants and metabolic alterations that can exacerbate chronic diseases, such as diabetes and hypertension. These results underscore the need to monitor the health of the inhabitants and control the sources of contamination.

Sodium and tungsten bronze nanorods have various applications, including use in devices capable of controlling indoor lighting and climate control.

The ingredient, extracted from the plant’s seeds, is a good source of protein and has a neutral flavor and aroma, making it easy to use in food products.

An experiment carried out by researchers from São Paulo State University on zucchini crops indicated that a 30% drop in rainfall would reduce the availability of calories in the sweet liquid that serves as food for pollinators, such as bees, by 34%, while extreme drought practically wipes out the resource. These results are particularly concerning for plants that depend on cross-pollination.

In animal tests, the molecule developed in South America has been shown to prevent fat accumulation and treat existing obesity and associated metabolic disorders. Initial human studies have confirmed the safety of the compound.

The assessment was made by Barbara Pompili, the French Ambassador for the Environment, at the opening of a forum at the National Museum of Natural History in Paris. The event is part of the FAPESP Week France program.