Patricia LoRusso, President of the American Association for Cancer Research (AACR), gave Agência FAPESP an exclusive interview during a visit to Brazil. She spoke about the importance of attracting early-career researchers to oncology, the future of clinical cancer research, and potential new discoveries in the field.
Bacteria, fungi and archaea living in the soil provide several ecosystem services, including carbon storage, and help restore native characteristics. The result contributes to advances in sustainable agriculture, one of the key points for this year’s G20 meetings.
The correlation between these two symptoms of the disease was observed by researchers affiliated with institutions in Brazil and France in a systematic review of 20 studies.
Described in the journal Scientific Reports, the research was conducted at SPARCBio, a center established by FAPESP and biological control company Koppert at the University of São Paulo’s Luiz de Queiroz College of Agriculture.
The device was developed by researchers at the University of São Paulo’s Heart Institute (INCOR) and a Brazilian company with FAPESP’s support. It is biocompatible and offers other advantages over the imported product used hitherto.
An electrode with films of iridium dioxide and niobium oxide on a titanium substrate removed molecules of the drug levofloxacin, considered an emerging pollutant.
The methodology was developed by Brazilian and British researchers, who tested it in Campinas, a large city in São Paulo state. Its aim is to optimize monitoring and combating the mosquito Aedes aegypti.
For three months, Brazilian researchers tracked 74 patients submitted to 12 sessions lasting 15 minutes each and observed remission of symptoms. The ancient Chinese practice had no side effects, according to an article on the study published in JAMA Network Open.
The producer is a company supported by FAPESP. It is developing an advanced three-phase recloser that isolates a section of the grid cut off by a tree fall and lets power be restored remotely.
Brazilian and British researchers analyzed data for 1,747 older participants tracked by ELSA over a period of 12 years, and mapped the different routes that can lead to a negative outcome. They advocate use of their findings by policymakers.
The event will take place in São Carlos (São Paulo state, Brazil) with FAPESP’s support. Twenty participants from Brazil and 20 from other countries will be selected.
The results of a study conducted by researchers at São Paulo State University (UNESP) could be highly positive for the future of the solar power sector.
Researchers at the Federal University of São Carlos found that glitter’s metal coating reduced the amount of light penetrating water bodies and hence impaired photosynthesis by the Large-flowered waterweed Egeria densa. The problem may impact primary producer organisms at the bottom of the food chain, they warn.
An interdisciplinary approach tested at the Federal University of São Paulo combined clinical, nutritional, psychological and exercise counseling. The intervention involved remote and in-person sessions, favoring adherence and lowering the cost to the health system.
The solution developed by the firm, with FAPESP’s support, permits controlled release of sterile males of Aedes aegypti in urban areas with the aim of reducing the population of these mosquitoes.
The report was written by 53 academic and government specialists, 12 young researchers, and 26 representatives of Indigenous and traditional communities. It aims to be useful to policymakers and to raise the general public’s awareness of the importance of protecting the ocean and coastline.
The event, which is supported by FAPESP, is for young researchers and environmental technicians. Thirty applicants from Brazil and 30 from other countries will be selected.
The opossum was found dead in a park in the center of Campinas, a large city in São Paulo state (Brazil), with the same viral variant as fruit-eating bats. These mammals are regularly detected in cities, where they are often attacked by dogs, so they can be considered sentinel species for infectious disease surveillance.
Researchers at the University of São Paulo analyzed data from 115 children who suffered from conditions considered syndromic (with several associated symptoms) and found a high incidence of overlapping genetic alterations. They argue that identification of genetic mutations can make diagnosis and treatment more accurate.
Blood pressure rose in offspring born to high-fructose rats, and physiological regulation of their cardiovascular system was impaired. High-fructose syrup is widely used as a sweetener by the food and beverage industry.
A study conducted in a poor suburb of São Paulo city (Brazil) analyzed how low-income communities deal with the hardships deriving from the economic crisis that began in 2014 and worsened during the pandemic.
Through experiments in roundworms of the species C. elegans, scientists at a FAPESP-supported research center showed that lifespan is reduced when RNA transfer between cells in different tissues is dysregulated.
A study by Brazilian researchers shows that the pigment is present not only in the seeds but also in other organs of Bixa orellana, the Annatto tree. They investigated the genetic pathways involved in synthesis of the substance.
A study led by Brazilian researchers suggests that the mechanism that exacerbates dengue infection following a case of zika differs from that acting on second-time dengue patients. The finding is relevant to the development of a zika vaccine.
A study conducted at a FAPESP-supported research center discovered a link between the protein VAPB and tumor cell proliferation in medulloblastoma, one of the most common and aggressive brain tumors in children.
Considered an invasive species, Sus scrofa causes damage to farmers in an important part of Brazil’s savanna-like biome. The researchers analyzed 55 landscapes in São Paulo state, observing larger numbers of native mammals in areas with well-conserved vegetation and diversified crops, while native species richness was far lower in areas of monoculture.
The analysis compared the effects of artepillin C on healthy cells and cancer cells, as well as the effects on its efficacy of variations in the medium’s pH.
With the new contributions from abroad, the Scientific Expeditions call, issued in partnership with the National Council for Scientific and Technological Development, now has a fund totaling some BRL 94 million.
CD4+ T cells play an important role in the immune response to pulmonary infections, but excessive amounts can damage the lungs. In experiments with mice, researchers at the University of São Paulo discovered what leads to this exacerbated response.
The startup has been supported by FAPESP since its foundation in 2020. The device can be used to make film for perovskite solar cells, biomaterials for wound dressings and tissue regeneration, and novel drug and cosmetic delivery systems.
Data from the Phase 3 clinical trial was published on February 1st in The New England Journal of Medicine. The vaccine is safe for both participants who have had dengue and those who have never been exposed to the virus before.
This part of the seafloor in the South Atlantic is rich in cobalt, nickel and lithium, as well as tellurium and other rare earths critical to the energy transition. The scientists plan to continue research on its natural processes as a contribution to prospecting efforts.
Developed by a team of Brazilian researchers, the device is made of plant-based material with little environmental impact, and detects pesticides in a few minutes, helping to certify food safety.
The aim is to foster scientific and technological collaboration between researchers affiliated with the Chinese entity and colleagues at universities and research institutions in São Paulo state.
André Morandini, Director of the University of São Paulo’s Center for Marine Biology, was on the team that has published a description of a rare medusa found at a depth of 812 meters. The animal has been sighted only twice in a deep-sea volcanic structure called Sumisu Caldera, in the Ogasawara Islands.
In 18 cities of the Barretos region, where the proportion of Black people in the population is smaller, cancer kills more members of this ethnic group, whereas in the capital of the same state, it kills more White people, according to a study that compares cancer mortality rates and points to ways of reducing inequalities in diagnosis and treatment.
The platform, developed by a company based in São Carlos (São Paulo state, Brazil) and supported by FAPESP, is able to predict and permit correction of failures in order to avoid unplanned factory production line downtime.
In experiments with rats, researchers at the University of São Paulo analyzed brain tissue and detected alterations in genes associated with energy metabolism.
The event will take place on July 16-26 at the University of São Paulo’s Physics Institute, for 100 graduate students and/or young researchers, half from Brazil and half from other countries.
In experiments with rats, researchers at São Paulo State University detected changes in the expression of more than 700 genes in offspring. One of these genes is known to be associated with prostate cancer.
The material is a compound similar to clay and enables inspectors to carry out in-situ assessment of structural conditions in buildings, bridges, dams and other structures without having to drill for samples and analyze them in a laboratory.
The two parties are interested in collaborative research on sustainable use of biodiversity in the Amazon, prevention of transmissible and chronic diseases, and sustainable construction, among other subjects.
Some species of cetacean are up to 4 meters in length, while others reach 30 meters. According to researchers at the State University of Campinas, genes that favor the colossal growth of these mammals also inhibit the development of cancer.
The study analyzed data for 13 Atlantic Rainforest restoration areas involving ten species of native trees that could be commercially useful to the timber industry. Publication of the findings comes during the UN Decade on Ecosystem Restoration.
Researchers at the University of São Paulo and São Paulo state’s Center for Epidemiological Surveillance observed spatial and temporal patterns of occurrence and co-occurrence for the two arboviral diseases in all Brazilian municipalities, alongside the influence of environmental and socio-economic factors.
Indonesia, Malaysia, Philippines, Singapore Thailand and Vietnam have dynamic economies and similarities with Brazil that make collaboration particularly relevant.