Researchers at the Federal University of São Paulo conducted experiments involving rats to analyze the effects of a high-fat high-sugar parental diet. The results suggested that ingestion of hypercaloric food by male progenitors favors weight gain and a build-up of body fat in their offspring.
The researchers correlated data on the animal’s ecological niche and connectivity among populations with existing and planned hydropower development sites in Brazil’s South region. They estimated that 30% of its habitat could be lost, heightening the risk of extinction.
A study conducted at the University of São Paulo helps explain why older people are more susceptible to the severe form of the disease and why it involves blood clotting disorders.
The fourth-generation particle accelerator installed at the Brazilian Synchrotron Light Laboratory (LNLS) was the topic for the 4th FAPESP Lecture 2023. LNLS Director Harry Westfahl Junior described the facility and the research opportunities it offers. He also announced the third call for proposals.
Researchers sampled oysters and mussels at three locations between the port of Santos and the nearby city of Guarujá. Their aims included assembling data as a basis for public policy on basic sanitation. The law does not currently require removal of microplastic particles from sewage.
Researchers at the Federal University of São Paulo analyzed saliva, oral microbiota and dental health of volunteers who were preparing for gastroplasty and after the operation. The results showed an increase in caries and periodontitis, as well as alterations in salivary inflammatory markers.
Applications of specialty glass range from astronomy to medicine, as well as data and power transmission. The study combined spectroscopy and computational modeling to show how the structure of the material is affected by addition of niobium oxide.
Technology developed with FAPESP’s support was the winner in the “Technological Innovation” category. Also, a University of São Paulo study that found a molecule capable of killing leukemic cells was awarded in “Oncology Research” category.
Available free of charge on the internet, the platform simulates fire propagation in the savanna biome three times a day and is in use in nine conservation units.
Heitor Cantarella was a member of BIOEN-FAPESP’s steering committee for 14 years. As a researcher at the São Paulo State Institute of Agronomy in Campinas, he has made groundbreaking contributions to efforts to reduce greenhouse gas emissions in agriculture.
In experiments with mice, researchers at the State University of Campinas observed alterations in feed consumption, weight gain, anxious behavior and an increase in central nervous system, adipose tissue and liver inflammation.
A study by researchers at the State University of Campinas and Harvard University shows that despite the presence of invasive strains of Saccharomyces cerevisiae, all of them belong to the ethanol fermentation environment, keeping the industrial process stable. Their findings can help cut costs and assure better results for producers.
With FAPESP’s support, the startup developed a smart biodressing produced by 3D printing and designed to accelerate skin wound healing. It will compete for a Global eAward in October.
A review of research on minimally processed vegetables highlights cases of unsatisfactory microbiological safety and calls for best practice assurance throughout the supply chain.
The project is the result of a partnership between FAPESP and Shell and could help make hydrogen a widely used fuel in Brazil. Hydrogen from a pilot plant to be built at USP using Raízen’s ethanol will power buses on the campus.
Researchers at the University of São Paulo investigated the effects of five concentrations of glitter on two strains of cyanobacteria. Use of the material in makeup, party costumes and decorations should be reconsidered, they argue.
A model developed by a cross-border collaboration including Brazilian researchers could help decision-makers assess the real impact of green roofs on the urban food-water-energy nexus.
In a study involving 46 volunteers, researchers at the Federal University of São Paulo found that telomere shortening, a biomarker of cellular aging, accelerated in untreated obstructive sleep apnea patients, whereas continuous positive airway pressure attenuated the damage.
Based on artificial intelligence techniques such as neural networks and machine learning, the system takes seconds to perform tasks that used to take months. It will extract useful information from the gigantic amount of data furnished by the new Vera C. Rubin telescope.
Experiments with rats at the Federal University of São Paulo suggest that the technique promotes reprogramming of the neurons affected by the disease, making them return to a normal state and interrupting seizures. Increased production of adenosine appears to play a key role in the process.
Researchers used magnetic resonance imaging to train a machine learning algorithm to help diagnose autism. The study involved physicists, statisticians, physicians and neuroscientists from centers in Brazil, France and Germany.
A project conducted by the Brazilian Agricultural Research Corporation (EMBRAPA) cross-referenced data from sensors to analyze soil and weather variations in the same vineyard so as to produce different wines and improve water and fertilizer management. Wineries in São Paulo state are already benefiting from the results.
A study published in Nature and led by scientists at Brazil’s National Space Research Institute (INPE) and Bristol University in the UK describes a novel methodology for calculating the carbon absorption capacity of recovering areas in the Amazon, Congo and Borneo, which contain the world’s largest tropical rainforests. Together these areas remove at least 107 million metric tons from the atmosphere every year.
A collaborative study by Brazilian and British researchers shows for the first time that obesity can cause a lack of vitamin D and not the other way around. The risk of vitamin D insufficiency and deficiency in subjects with abdominal obesity was 36% and 64% higher respectively than in those without.
A biocatalyst discovered by Brazilian researchers has the potential to increase renewable biofuel output by removing obstacles in technology and production processes, as well as enhancing the manufacturing of bioplastics and biopolymers.
Primates in a Brazilian national park spend 41% of their time on the ground. Territoriality influences stone tool use, the behavior of females while on heat, and care of disabled individuals.
Genome sequencing of clinical samples from a child hospitalized in Aracaju, the capital of Sergipe state (Brazil), revealed the simultaneous presence of the protozoan Leishmania infantum and an as-yet unnamed parasite belonging to the genus Crithidia, identified earlier in a fatal case of visceral leishmaniasis in the same region.
Photodynamic therapy developed by the Center for Research in Optics and Photonics, which is supported by FAPESP, has been recommended by Brazil’s federal body responsible for including novel healthcare technologies in the national health service.
Researchers at the University of São Paulo analyzed inflammatory markers in cyclists who trained regularly and had been exposed to traffic-related pollution. The results of the experiment, which was conducted in São Paulo city, are published in the American Journal of Physiology.
The aim of the study is to understand the strategies used by children and young people in low-income households to adapt to the public health crisis and economic hardship in the UK, South Africa and Brazil.
The innovative approach highlights vulnerability to deforestation, fire and drought, as well as poverty. The results can help formulate public policies for sustainable development.
A study combining genetic analysis and oceanographic simulations showed that a species of mangrove rarely disperses very far, so that North and South Brazil have two distinct populations. The results can help prioritize conservation units and understand global patterns in mangrove forest formation.
An investigation covering four different parts of Brazil carried out analysis of genomic data from 34 fossils, including larger skeletons and the famous mounds of shells and fishbones built on the coast, and revealed differences between communities. An article on the study is published in Nature Ecology & Evolution.
Brazilian scientists analyzed the typical soil composition resulting from native management with the aim of developing biotech applications for more effective restoration of degraded areas.
The first-ever study of dark kitchens conducted in Brazil collected data on 22,520 establishments located in three cities in São Paulo state and listed by iFood. An article on the study offers a profile of these delivery-only restaurants, which proliferated during the pandemic.
Modeling projections depend on the installation of networks specific to these areas in Brazil and the Andes, where the available data falls far short of what is needed.
Research conducted in manipulated sugarcane plots showed that small water bodies such as ponds and puddles can contribute to sustainable farming even with environmentally hostile practices.
One of the goals of the study conducted by scientists at the Center for Development of Functional Materials and the Center for Innovation on New Energies is to reduce atmospheric emissions of this greenhouse gas.
A team affiliated with a FAPESP-supported research center showed in mice that molecules capable of preventing the peptide C5a from binding to its cellular receptor helped prevent lung damage and other complications typical of severe COVID-19.
An article in Science by 35 researchers affiliated with institutions in Brazil and elsewhere shows that carbon emissions resulting from forest degradation are equivalent to emissions from deforestation. The authors analyzed degradation due to fire, edge effects, illegal logging and extreme drought.
The results pave the way for breeding of cattle with selected traits. Preliminary work findings for human embryo models recently published by international groups could contribute to the understanding of congenital defects and early pregnancy loss.
In experiments conducted at the State University of Campinas (Brazil), intestinal epithelial stem cells proliferated more in mice fed an inulin-rich diet than in mice given insoluble fiber. The study also showed that the beneficial effects depended on interaction with gut microbiota.
Scientists at Brazilian Center for Research in Energy and Materials (CNPEM) investigated enzymes produced by two species of fungus used to break down sugarcane bagasse for production of second-generation ethanol. The goal of the project is to increase the efficiency of this process, which currently depends on imported feedstocks.
Similar programs and FAPESP’s pragmatism arouse interest in intensifying collaboration and joint calls for proposals involving research centers in Switzerland and São Paulo.
A study conducted at the University of São Paulo and reported in PNAS explains hyperglycemia in hospitalized patients and shows how SARS-CoV-2 causes symptoms similar to those of diabetes.
Strategies for reconciling forest conservation and income generation for families living on Chico Mendes Extractive Reserve in Acre state are the focus of a project in which local scientists are collaborating with colleagues from the states of São Paulo and Pará. The project is part of the Amazon+10 Initiative.
An article by scientists at the Federal University of São Paulo shows that the South and Southeast of Brazil are the most affected regions, and that Espírito Santo is the state most affected by waves of heat and cold.
Researchers at Butantan Institute in São Paulo, Brazil, discovered that survival of the parasitic worm that causes the disease depends on expression of a specific type of RNA. In animal trials, inhibition of the molecule interrupted the infection.