Four substances isolated from Mimosa caesalpiniifolia were found to be more effective against thrush and candida than was fluconazole, the drug usually prescribed to treat the disease. Brazilian researchers are developing an ointment.
Using a systems biology approach, Brazilian researchers identified several genes that can be explored as therapeutic targets and as biomarkers of predisposition to chronic joint pain.
Model predicts genetic traits that make Nellore cattle, Brazil’s main beef breed, more resistant to environmental changes that affect herd productivity.
Tool developed by Brazilian researchers can be used to study disease mechanisms, plant physiology and structures of large cities, among other applications.
Color differences in the light produced by the larviform beetle are known to be caused by two enzymes with minor structural differences, but the details were hitherto unknown. This discovery has potential for applications in biotechnology.
An article published in Nature Communications shows that three species of electric eel exist, not just one as previously described, and that one of them produces an electric shock up to 860 volts. The researchers were funded by FAPESP, the Smithsonian and National Geographic.
Genetic profiles of microorganisms isolated from patients with urinary tract infection display a high degree of resistance and virulence. The superbug KPC was found in samples.
Reports launched by the Brazilian Platform on Biodiversity and Ecosystem Services estimates that forest restoration on this scale would sequester 1.39 million tons of CO2 and increase biodiversity conservation by 200% without adverse impacts on agriculture.
A study by researchers at the Center for Cell-Based Therapy, which is supported by FAPESP, identified microRNAs involved in pluripotency maintenance and cell differentiation. The discovery paves the way to the development of drugs capable of making ESCs regress to the earliest stage of development.
In a study supported by FAPESP, experiments with mice showed the anti-inflammatory drug mefenamic acid to be more efficacious than praziquantel, the only drug available to combat the disease.
Study conducted to test a procedure based on ionization of atmospheric air eliminates 99% of Candida albicans fungus that causes hospital-acquired infections, without generating toxic waste.
Brazilian researchers studied the feasibility of a space maneuver that could be used to change the course of satellites and even send spacecraft beyond the Solar System with less fuel.
Water shortages cause economic losses for industry and agriculture, among other sectors, as well as damage human health, warns a report issued by the Brazilian Platform on Biodiversity and Ecosystem Services.
Particles originated in forest fires in the Center-West and North of Brazil interacted with clouds borne by the cold front coming from the south, causing sky and rain to turn to a dark-grey hue.
Participants at the São Paulo School of Advanced Science on Learning from Data warn that because minorities have less access to services that generate data, they tend to be underrepresented in databases used for machine learning projects.
Experiments performed in Brazil show that systematic eradication of plants contaminated by cowpea aphid-borne virus (CABMV) can keep orchards producing for at least 25 months and avoid annual replanting.
Stars, galaxies and black holes that began to form approximately 30 million years after the Big Bang were discussed during a course supported by FAPESP and held in Brazil to prepare researchers for the next stage in world-class astronomy.
Theoretical findings in a study performed by researchers with FAPESP’s support and published in Scientific Reports could be exploited in the development of quantum computing.
Brazilian researchers observed the association only in subjects who consumed more than three small cups of coffee per day. Moderate consumption, however, appears to have beneficial effects on the cardiovascular system.
Vanderlei Martins, a professor at the University of Maryland and former FAPESP grantee, is responsible for the device, developed in partnership with NASA. Martins spoke about the project to the São Paulo School of Advanced Science on Atmospheric Aerosols, which was funded by FAPESP.
Mountain range uplift, river formation and other events that occurred 30 million years ago explain the emergence of new species of the arachnid in the biome’s southernmost portion, according to a Brazilian study.
A FAPESP-funded study with results published in The Lancet Infectious Diseases has identified markers capable of predicting mortality in patients with symptoms of yellow fever, potentially helping to prevent the development of severe conditions.
A study conducted as part of a Thematic Project by Brazilian and US researchers investigates how plants and animals in the Atlantic Rainforest biome have reacted to climate change in past millennia.
Professor at University of São Paulo and Harvard Medical School leads a project funded by FAPESP via its São Paulo Excellence Chair (SPEC) program to find neurophysiological biomarkers that will improve the rehabilitation of patients with motor disabilities.
Brazilian startup wants to supply manufacturers of chemicals and foods with bioproducts that do not harm human or animal health and are produced by sustainable industrial processes.
Guaranteeing stable funding is key if Brazilian researchers are to use the scientific instruments that will become available in the years ahead, according to experts at the Annual Meeting of the Brazilian Society for the Advancement of Science.
The results of a clinical trial published in the journal Appetite show that transcranial direct current stimulation can reduce or increase appetite, depending on the patient’s genetic profile.
An international study with key contributions from Brazilian researchers shows that an endangered species, famed as a “forest gardener,” influences African forest composition in terms of tree species and increases the aboveground biomass over the long term.
A study analyzing data from almost 30,000 nurses shows that the effects of physical activity throughout life are cumulative. Collaboration between Brazilian and US scientists demonstrates the importance of exercise before adulthood.
Extension of the moratorium to the Brazilian savanna would prevent the loss of 3.6 million hectares of native vegetation that risk being converted into soybean plantations by 2050, according to a study published in Science Advances.
The virtual platform enables R&D personnel in the pharmaceutical, cosmetics, agribusiness and fine chemical industries to obtain toxicological and ecotoxicological assessments remotely without needing to have their own labs.
Experiments with mice performed within the scope of a FAPESP-funded study show that a substance derived from cannabis plants attenuates isolation-induced aggressive behavior.
A study of individuals over 65 years old showed that all-cause mortality risk increased nearly 63-fold in women with low appendicular muscle mass. The risk of dying increased 11.4-fold in men.
FAPESP’s policy of open access to scientific publications requires the use of institutional repositories to increase the visibility of science supported by the Foundation without interfering with researchers’ freedom to choose journals.
A FAPESP-funded study investigated behaviors associated with weight gain and cardiometabolic risk in adolescents. Missing the first meal of the day can contribute to the development of unhealthy habits and behaviors.
Brazilian researcher studied LHC experiment and found a signature highly similar to that of quark-gluon plasma in lead atom proton collision. Previous studies were based on collisions of heavy nuclei.
X-ray imaging shows that nanostructured silica acts as protective vehicle to deliver antigen intact to intestine so that it can trigger an immune response. Material developed with FAPESP funding could give rise to polyvaccine against six diseases.
Simplified low-cost method is as accurate as most advanced sequencers in analyzing medulloblastoma, enabling personalized treatment to be prescribed in developing countries.
Researchers find that substances synthesized from plant species endemic to the biodiversity hotspot can kill the parasites that cause these neglected diseases.