Researchers classify 258 protected areas in Brazil as “moderately vulnerable” and 17 as “highly vulnerable”. Areas at greatest risk are in the Amazon, Atlantic Rainforest and Cerrado biomes.
Tests in rats showed enhanced efficacy of the drug as well as the absence of side effects, such as stomach bleeding. This innovation could be used to treat temporomandibular joint inflammation.
Researchers in Brazil altered the chemical structure of alkaloids from cat’s claw, aiming to obtain more potent compounds for the treatment of tumors and inflammations; scientists plan to develop a modified strain of U. guianensis and use its own metabolism to scale up the production of therapeutic compounds.
Brazilian researchers calculated the amount of nutrients in sugarcane leaves, which are normally left on the ground after harvest, and the equivalent in fertilizer required to maintain crop yield if the straw is removed.
Larvae of a fungus gnat found in Iporanga, São Paulo State, Brazil, have bioluminescent properties previously observed only in species native to North America, New Zealand and Asia. This study paves the way for new biotech applications.
Systems that assess and train decision-making skills have been developed by a startup supported by FAPESP and tested on athletes belonging to top-tier Brazilian sports clubs. The researchers responsible say the technology can also be used in sectors such as healthcare.
An international group of ecologists contests an article published in Science, which among other controversial statements proposed “reforestation” of the Cerrado, Brazil’s savanna biome.
USP has been chosen to partner with the new Engineering Research Center, which will start operating in 2020, with an investment of up to USD20 million in ten years.
A report published in PLOS ONE describes key roles of various microorganisms in the development of the larvae of Scaptotrigona depilis. Researchers warn that this symbiotic relationship is threatened by the indiscriminate use of pesticides.
Construction of hydroelectric dam contributed to rise in cost of living and electricity for local population, and exacerbated problems in housing, water supply and sanitation, according to study supported by FAPESP.
Technology created by startup with FAPESP’s support helps customize formulations of microorganisms that promise to enhance livestock health and performance.
Patient with advanced refractory lymphoma was treated in Brazil by researchers at a center funded by FAPESP. The technique known as CAR T-cell therapy was used for first time ever in Latin America.
Research reported in Physical Review Letters presents the detection of energy transfer from excited electrons to the crystal lattice on the femtosecond timescale. Knowledge could contribute to the development of materials that prolong the coherence time.
Paper endorsed by 407 scientists in Brazil estimates the value of ecosystem services linked to nature conservation, such as pollination, pest control and water security.
A system of cameras tracks eye movements, processes images and inputs them into a computer, where special software translates the data and sends commands to telemetry-controlled devices.
This FAPESP-supported School of Advanced Science discussed how applications of modeling to nonlinear dynamic systems have helped to predict effects such as vibration in civil engineering structures and dispersion in drug delivery.
Scientists show that CRP3, normally produced in arteries, is expressed in saphenous vein grafts following coronary artery bypass surgery. The finding suggests that this molecule participates in adaptation to the increased blood flow and pressure resulting from arterialization.
Researchers tested a material known as polyether siloxane, a flexible transparent hydrogel that can absorb large amounts of water without dissolving and is ideal for controlled-release drug delivery.
Phylogenomic analysis shows that pathogen isolated in Brazilian hospital does not belong to the genus Leishmania. Researchers are investigating whether this species alone can cause severe disease or intensifies symptoms in co-infected patients.
Researchers at a Research, Innovation and Dissemination Center supported by FAPESP have created a composite with antifungal properties that are 32 times greater than those of silver by irradiating a metallic tungstate with electrons and femtosecond laser light.
Oxide plays a key role in cardiovascular and neurodegenerative diseases as well as cancer. Experiments reveal a hitherto unknown mechanism underlying the formation of nitroso thiols.
Brazilian researchers find that digit tips regrow after amputation because they consist of skin, bone and nail, three types of tissue that recover naturally when damaged.
At the São Paulo School of Advanced Science on Science Diplomacy and Innovation Diplomacy, rectors of the state of São Paulo’s leading public universities reaffirmed the importance of collaboration to the strengthening of international academic ties.
Compound inhibits key enzymes, interrupting the parasite’s lifecycle in human organisms and preventing transmission to vector insects. This discovery published in Science involved researchers funded by FAPESP.
Blood sugar levels in obese mice were controlled more efficiently when the mice were challenged with a glucose overload and treated with 12-HEPE, a lipid produced in response to cold by brown adipose tissue.
Developer of a bactericidal and antimicrobial solution for the increasing of product shelf life, Nanox was supported by FAPESP through its Innovative Research in Small Business Program.
Four substances isolated from Mimosa caesalpiniifolia were found to be more effective against thrush and candida than was fluconazole, the drug usually prescribed to treat the disease. Brazilian researchers are developing an ointment.
Using a systems biology approach, Brazilian researchers identified several genes that can be explored as therapeutic targets and as biomarkers of predisposition to chronic joint pain.
Model predicts genetic traits that make Nellore cattle, Brazil’s main beef breed, more resistant to environmental changes that affect herd productivity.
Tool developed by Brazilian researchers can be used to study disease mechanisms, plant physiology and structures of large cities, among other applications.
Color differences in the light produced by the larviform beetle are known to be caused by two enzymes with minor structural differences, but the details were hitherto unknown. This discovery has potential for applications in biotechnology.
An article published in Nature Communications shows that three species of electric eel exist, not just one as previously described, and that one of them produces an electric shock up to 860 volts. The researchers were funded by FAPESP, the Smithsonian and National Geographic.
Genetic profiles of microorganisms isolated from patients with urinary tract infection display a high degree of resistance and virulence. The superbug KPC was found in samples.
Reports launched by the Brazilian Platform on Biodiversity and Ecosystem Services estimates that forest restoration on this scale would sequester 1.39 million tons of CO2 and increase biodiversity conservation by 200% without adverse impacts on agriculture.
A study by researchers at the Center for Cell-Based Therapy, which is supported by FAPESP, identified microRNAs involved in pluripotency maintenance and cell differentiation. The discovery paves the way to the development of drugs capable of making ESCs regress to the earliest stage of development.
In a study supported by FAPESP, experiments with mice showed the anti-inflammatory drug mefenamic acid to be more efficacious than praziquantel, the only drug available to combat the disease.
Study conducted to test a procedure based on ionization of atmospheric air eliminates 99% of Candida albicans fungus that causes hospital-acquired infections, without generating toxic waste.
Brazilian researchers studied the feasibility of a space maneuver that could be used to change the course of satellites and even send spacecraft beyond the Solar System with less fuel.
Water shortages cause economic losses for industry and agriculture, among other sectors, as well as damage human health, warns a report issued by the Brazilian Platform on Biodiversity and Ecosystem Services.
Particles originated in forest fires in the Center-West and North of Brazil interacted with clouds borne by the cold front coming from the south, causing sky and rain to turn to a dark-grey hue.
Participants at the São Paulo School of Advanced Science on Learning from Data warn that because minorities have less access to services that generate data, they tend to be underrepresented in databases used for machine learning projects.
Experiments performed in Brazil show that systematic eradication of plants contaminated by cowpea aphid-borne virus (CABMV) can keep orchards producing for at least 25 months and avoid annual replanting.
Stars, galaxies and black holes that began to form approximately 30 million years after the Big Bang were discussed during a course supported by FAPESP and held in Brazil to prepare researchers for the next stage in world-class astronomy.