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The new cutoff values for a metric widely used by geriatricians, physical therapists and nutritionists are more accurate, facilitate early diagnosis and contribute to preventive treatment.

The law disciplines Brazil’s actions as a provider but not as a user of genetic resources from other countries, researcher Bráulio Dias noted during an online seminar held by FAPESP.

A study by the University of São Paulo has discovered that when macrophages engulf cells infected by the novel coronavirus, they begin producing excessive amounts of pro-inflammatory molecules, and their capacity to recognize and phagocytize dead cells is reduced twelvefold.

Brazilian researchers monitoring the population of metropolitan São Paulo have reported atypical cases in which SARS-CoV-2 continues to replicate in the organism for longer than the recommended isolation period.

A method created in Brazil by the Human Genome and Stem Cell Research Center could be used for large-scale production of livers for transplantation.

The scientists detected incapacities related to gait timing and foot placement. Their discoveries serve as a basis for the development of an exercise protocol that mitigates the difficulty.

The platform developed by researchers from Brazil and Chile lets users view geolocation of cases, deaths and vaccinations over time.

By means of specific biomarkers, a diagnostic test developed by the Brazilian startup Onkos shows whether a lump in the gland is benign or malignant, reducing the risk of unnecessary surgery.

Brazilian researchers treated cells infected by SARS-CoV-2 with compounds produced by gut microbiota from dietary fiber. The intervention did not mitigate viral replication but reduced expression of a gene that plays a key role in viral entry into cells and a receptor involved in the inflammatory process.

In an online seminar hosted by FAPESP, researchers from Brazil, the United States and France analyzed the impact of the pandemic on educational inequality.

Extracorporeal membrane oxygenation (ECMO) can keep patients alive until the disease recedes.

Luciferin-luciferase system developed in collaboration with Japanese researchers produces brighter and longer-lasting far red light. The innovation can be used to image cells and tissues for diagnosis and biomedical research.

Researchers analyzed socioeconomic and environmental indicators for the 180 municipalities in the mega-region around São Paulo state capital, detecting environmental inequity and dependency.

Brazilians are working in more than 60 scientific fields in over 50 German cities. An online event hosted by the Brazilian Embassy in Berlin featured researchers and representatives of institutions.

Laboratory trial by Butantan Institute in partnership with the University of São Paulo involved inoculation of variants P.1 and P.2 into cultured cells containing blood serum from vaccinated subjects. The results were satisfactory, according to the researchers.

The technology uses ultraviolet-C, which can inactivate the novel coronavirus. Startup BioLambda was supported by FAPESP and partnered with the Albert Einstein Jewish-Brazilian Hospital in São Paulo.

Brazilian researchers tested the capacity of different materials to produce sensors for the detection of PCA3, a gene that is overexpressed in prostate cancer. The technique can also be used to diagnose infectious diseases, including COVID-19.

In a study of the effects of cigarette smoking on exacerbation of the disease, scientists at a FAPESP-supported research center identified a novel pathway in the inflammatory process relating to bone damage.

Group affiliated with a FAPESP-supported research center showed that the parasite blocks the action of an enzyme using autophagy.

This is the conclusion reached by two modeling studies posted recently by Brazilian scientists to the preprint platform medRxiv.

Published by an Anglo-Brazilian epidemiological research center, the study revealed that in only seven weeks SARS-CoV-2 lineage P.1 became the most prevalent strain of the virus in Manaus. Analysis of more than 900 samples from patients diagnosed in the period pointed to a higher viral load.

Blood plasma from COVID-19 convalescents was tested against Brazilian variant isolates obtained from patients diagnosed in Manaus. The study also assessed the effectiveness of plasma from volunteers immunized with CoronaVac.

In Araraquara, state of São Paulo, researchers detected the P.1 variant in 93% of samples from patients diagnosed at a primary healthcare facility in the first two months of the year.

Developed by researchers at the University of São Paulo, the non-invasive methodology facilitates identification of immature or poor-quality seeds without destroying them or creating residues.

Article published by Brazilian researchers in Sports Medicine presents a systematic review of scientific studies on the topic.

In a study conducted at the University of São Paulo, researchers used infrared laser irradiation to accelerate the activity of enzymes immobilized on gold nanoparticles. The technique could have biomedical and industrial applications.

Study conducted at University of Campinas in collaboration with University of Michigan explains nanoscale physics of this manmade material in article published in Science Advances.

Open-access repository established to facilitate research on the disease holds anonymized data including clinical examinations and laboratory test results from 485,000 patients processed by five institutions.

Study suggests that replacing native vegetation with pasture or crops increases competition among microorganisms, favoring those with antimicrobial resistance genes. Brazilian scientists advocate more research to find out whether bacteria can migrate to food and reach humans.

Study conducted at a FAPESP-supported research center shows that anti-inflammatory peptide TnP could lead to drug development.

In an article published in BMC Biology, Brazilian researchers compare the phenomenon observed in the species E. coli to a “tragedy of the commons”, in which individual interests take precedence over the collective good. According to the authors, it masks the emergence of bacterial variants and makes the colony’s mutation rate appear lower.

Agricultural residues already produce 25% of the electricity used by households in the state. The proportion could jump to 70%, according to researchers who took part in an online seminar on the topic.

There is no universally adopted system or standard for collecting, documenting and sharing the massive amount of data from research on the disease, noted an expert who took part in the Second Latin American and Caribbean Scientific Data Management Workshop.

Researchers in Brazil, Argentina, Chile, and the UK are participating in the initiative. Results are published in the journal BioScience.

The use of CAR T-cells reprogrammed to “recognize” Cryptococcus spp. proved effective to combat the infection in vitro and in mice.

Study by researchers at the University of Campinas published in Physical Review Letters discusses both light dispersion by vibrations inside the device and light dissipation to the exterior, an aspect rarely studied hitherto.

In October the CDC recommended ten instead of 14 days of isolation for patients with mild or moderate symptoms, but Brazilian researchers found viable viral particles in 25% of samples collected from patients on the tenth day of symptoms.

Operating in the São José dos Campos Technology Park, Autaza’s RIC has an optical system for automotive paint quality inspection using computer vision and artificial intelligence.

Researchers at the University of São Paulo estimated biodiversity and biomass losses in the biome using data from 1,819 forest inventories. In terms of carbon storage, the losses correspond to the destruction of 70,000 km² of forest, representing some USD 2.6 billion in carbon credits.

Scientists will monitor areas in which these diseases are endemic, such as São Paulo, the Amazon, the Pantanal and Panama, to investigate the factors that trigger outbreaks.

Scientists who study capuchin monkeys on a nature reserve in Brazil found that stone tools are used for digging, seed pounding, and stone-on-stone percussion. The monkeys can serve as a model to help understand how humans evolved to use tools.

Researchers describe a scenario in which randomly distributed non-polarized metal “puddles” are immersed in a polarized insulating matrix.

With FAPESP’s support, PangeiaBiotech develops genetically modified varieties of sugarcane that are protected against attacking insects and glyphosate-tolerant.

The black and white tegu lizard, which depends on external environmental factors to regulate body temperature, can survive swings between 15 and 35 degrees Celsius in a single day while keeping blood pressure steady. This study extends scientists’ knowledge of cardiovascular regulation in vertebrates.

An analysis conducted in the Brazilian state of São Paulo detected seven proteins in plasma from hospitalized patients that could be used in novel treatments and methods of identifying potentially severe or critical cases.

The different criteria used in Phase 3 clinical trials of the vaccines approved so far were explained by scientists in a webinar hosted by FAPESP. The impact of delays in vaccinating Brazilians was one of the topics discussed.

The new Applied Research Center’s mission is to conduct research that can provide input for public policies. FAPESP is partnering with the Maria Cecilia Souto Vidigal Foundation and INSPER to mount the initiative.

According to a paper by Brazilian researchers published in Nano Today, the spatial arrangement of proteins on the surface of SARS-CoV-2 assures highly efficient interaction with target receptors on human cells.

In an article published in Scientific Reports, Brazilian researchers show that besides simplifying operational logistics and improving production, fertilization of the grass used as a cover crop can reduce fertilizer use in the long run.

Startup supported by FAPESP has developed equipment for biological control of pests that affect soybean and cotton production.