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The presence of Candida auris in a hospital in Salvador, Bahia, was confirmed at end-2020 and reported in an article in the Journal of Fungi. The fungus can cause a lethal invasive disease and is ringing alarm bells because of the speed with which it develops drug resistance.

Brazilian researchers show that a combination of inflammatory cytokines in the blood and cannabis use, daily or during adolescence, heightens the odds of developing psychiatric disorders.

Fewer Atlantic mangrove fiddler crab embryos survived in a warmer, more acid environment mimicking conditions forecast for the end of this century. Given the important ecological role of this invertebrate in mangroves, the researchers warn of a potential cascade effect.

Researchers at the University of São Paulo discover that the fungus Fusarium verticillioides uses volatile compounds to manipulate insects and plants, promoting its own dissemination.

The system, developed by a startup supported by FAPESP, in partnership with researchers at the University of Campinas, helps plantation managers choose the optimal time to harvest the crop.

Researchers at the University of São Paulo conducted experiments with blood plasma from 60 volunteers infected in 2020 by SARS-CoV-2 lineage B.1.1.28. In 84% of cases, antibodies in the samples neutralized the Gamma variant in cultured cells.

Supported by FAPESP and led by a researcher at the Federal University of São Paulo, EPICOVID-19 BR 2 tested 120,000 people in 133 cities between January 25 and April 24, 2021. Amazonas was the state with the highest seroprevalence, with positive test results accounting for 31.4%. The nationwide average was 15%.

An Anglo-Brazilian research center analyzed samples from blood donors tested for antibodies against the novel coronavirus.

The discovery, made possible by a partnership between a research group and a startup in São Paulo state (Brazil), could lead to novel treatments for intracranial hypertension and its complications, such as stroke.

A group at the University of Campinas used protein mapping to show how abnormal levels of the neurotransmitter glutamate impair the functioning of neurons and oligodendrocytes. The findings could serve as a basis for more effective treatment.

The device was used for the first time to culture two maternal endometrial cell types, revealing the effects of alterations in glucose and insulin levels in the uterine environment. It can also be converted into a model for study of pregnancy in humans and endometriosis.

Researchers describe how fumiquinazoline C is synthesized and investigate its function in conidia, asexual non-motile spores of the fungus Aspergillus fumigatus that can cause severe infections in immunosuppressed patients. The discovery could lead to the development of novel medications.

Illegal logging to clear land for cattle grazing has fueled growth in Brazil’s greenhouse gas emissions, according to participants in a webinar on the prospects for COP26 hosted by FAPESP.

The largest series of autopsies ever performed on children who died from COVID-19 showed that the ability of the novel coronavirus to invade and damage the tissue of all major organs is one of the factors leading to multisystem inflammatory syndrome in children (MIS-C).

Hybrid material made from magnetite nanoparticles sticks to contaminants and can be removed from water by a magnet. The technique can be adapted for use in removing synthetic dyes, drugs, hormones and pesticides.

Models for professional use were the most effective at retaining aerosol particles of a size equivalent to the novel coronavirus, followed by TNT masks sold in drugstores. The efficacy of fabric masks ranged from 15% to 70%. A tight fit and lack of seams enhanced protection.

Patients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80, according to a study by Brazilian researchers.

Cities located in metropolitan areas of this Brazilian state score better according to an index that measures the existence of public policies designed to adjust critical sectors to the impacts of climate change.

The study shows that the 2019-20 drought resulted from a natural meteorological phenomenon similar to the one that caused the 2014-16 critical water shortage in São Paulo state, Southeast Brazil.

The call aims to advance knowledge of the societal effects of the COVID-19 pandemic and solutions to mitigate them. The submission deadline is July 12. Eligibility checking ends June 14.

A research group at São Paulo State University (UNESP) analyzed how Candida albicans fungi and Staphylococcus aureus bacteria influence gene expression and tumor cell survival.

The study was conducted in a Brazilian national park and was based on analysis of tree rings in the species Amburana cearensis, as well as satellite images.

With support from FAPESP via its program to fund innovative research, the startup has developed a rejuvenating serum based on bioactives obtained from sweet wormwood, a plant used in traditional Chinese medicine.

Brazilian researchers studied the case of identical twins in which only one sibling was reinfected and developed complications after a second exposure to the virus. Their analysis showed that the adaptive immune response can be different even between individuals with the same genome.

The study showed that interdisciplinary action facilitates weight loss, improves quality of life and eating behavior, and reduces symptoms of depression.

A call for proposals issued jointly with the Ministry of Science, Technology and Innovation and the Brazilian Internet Steering Committee selected the new research centers, which will focus on health, agriculture, manufacturing, and smart cities.

Trials performed by researchers at the University of São Paulo with healthy young adults show that the right level of protein intake is the key to muscle health, regardless of protein source.

Strategies to increase funding for action-oriented research that helps make societies and economies more resilient, equitable and sustainable were the focus for the Second Global Forum of Funders, held online on April 26-28.

Workers with blood lead levels below the legal ceiling in Brazil expressed a microRNA associated with a decrease in DNA methylation, a physiological process required for the organism to be in balance. However, known clinical manifestations occur when levels are high.

This is the main finding of a study published in Clinical Infectious Diseases. The authors analyzed blood samples collected in a town in the Brazilian Amazon before and after the first wave of the pandemic to detect the presence of antibodies against dengue virus and SARS-CoV-2.

A study by scientists at a FAPESP-supported research center analyzed genetic material from 86 couples in which only one spouse was infected. The results suggest that more frequent variants in the resistant spouses could lead to more efficient activation of natural killer (NK) cells, which are part of the innate immune system, the first barrier against infection.

The research group created a virus capable of acting on specific adult brain regions, helping to elucidate the role of key neurons in the prefrontal cortex. They tested the technique on mice.

Conclusion was drawn from a study that involved 92 adolescents aged 11-18. The findings underscore the importance of considering differences between the sexes when treatment is planned.

Whole mitochondrial DNA sequencing of the three extant species of the aquatic mammal shows that they first split from their common ancestor after geological events isolated the South American region from the sea. The African species may have originated in migration borne by marine currents.

A review article by Brazilian researchers shows that alterations in the defense cell metabolism may explain why many patients who survive sepsis die within a year or suffer from long-term complications

Brazilian scientists conducted preclinical trials to test membranes produced from mesenchymal stem cells that can differentiate to cartilage and promote local immunoregulation.

A mutation in the variant’s spike protein is associated with glycosylation, which prevents antibodies from binding strongly to the virus. If the discovery is confirmed by further research, it could serve as a basis for future vaccines that are more effective against novel variants.

According to researchers affiliated with the University of São Paulo, these indicators can orient preventive care for the most vulnerable and rehabilitation for survivors who suffer from long-term complications.

In an article published in PLOS ONE, scientists at a FAPESP-supported research center describe the impact of hypoproteinemia on the expression of microRNAs associated with kidney development in rat embryos.

Brazilian researchers show that feed supplementation improves fatty acid profile of milk and promotes a healthier omega-6/omega-3 ratio.

Researchers at the University of Campinas in Brazil reveal the mechanisms whereby SARS-CoV-2 disrupts the regulation of inflammation, coagulation and blood pressure when it infects alveolar cells, responsible for gas exchange in the lungs.

Researchers analyzed the effects of wildfires on plant cover and soil quality in the last 40 years. The findings of the study show that the forest is highly vulnerable even in well-conserved areas far from the ‘deforestation arc’.

Sample collection is much easier and less invasive. Self-collecting is feasible, depending on the child’s age. Schools should reopen only with mass testing to keep track of asymptomatic cases, the researchers argue.

People with diseases such as rheumatoid arthritis and lupus are more likely to have heart attacks, angina, and strokes. A review of the scientific literature on the subject shows that regular exercise improves vascular function in these patients.

A multinational research group used data from São Paulo to perform calculations which suggest that even a minor reduction in the city’s mobility – equivalent to a rise from 45% to 50% in the social distancing index – correlates with a considerable fall in new infections and deaths after a few days.

A simple and affordable solution developed by researchers at the University of São Paulo and a Nigerian collaborator eliminates even multi-resistant bacteria. Clay, papaya seeds and banana peel are among the raw materials used by the group.

Butterflies are considered a key biological indicator of trends in the biome. The study quantified the contributions of landscape and climate variables to current species distribution patterns.

Inexpensive test is non-invasive and based on detection of bladder cancer biomarkers in urine.

Infection of periodontal tissue, not just airways, explains the high viral load found in the saliva of COVID-19 patients, this study suggests.

An electrical impedance tomography system developed by a Brazilian company enabled critical care staff at a hospital run by Harvard University to adopt individualized mechanical ventilation strategies and reduced the need for extracorporeal membrane oxygenation (ECMO) therapy