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Research by the FAPESP-funded Center for Metropolitan Studies (CEM) shows that it is not feasible to separate high-risk groups in low-income communities, where the majority of the Brazilian population live. The problem is especially acute in the Southeast region, with metropolitan São Paulo displaying the largest deficit.

One of the studies will evaluate the effectiveness of drugs that inhibit bradykinin against pulmonary inflammation in critical patients. The other will analyze the transmission dynamics of the novel coronavirus in a small town in Amazonia.

Species never before found in humans described in PLOS ONE belong to the genera Ambidensovirus and Chapparvovirus. Researchers do not yet know if they can cause disease.

Groundbreaking study shows that regular exercise in prepubertal childhood improves the functioning of cells essential to vascular health. Babies weighing less than 2.5 kg at birth are more likely to develop cardiovascular diseases in adulthood.

Scientists in the state of São Paulo are working on a method of diagnosing the disease quickly and cheaply by combining an analysis of the pattern of molecules in body fluids with machine learning.

Scientists at Brazil’s National Energy and Materials Research Center are analyzing the antiviral action of commercially available drugs in cultured cells.

Researchers explains how their experience with the Zika virus, made possible with funding from FAPESP, helped them to cultured the SARS-CoV-2 coronavirus.

A population study conducted at a regional center of the state of São Paulo (Brazil) showed that 32.9% of subjects under 40 had no immunity against the disease, compared with only 1% in those over 50.

Research and higher-education institutes from the state of São Paulo have signed an agreement with the Oak Ridge National Laboratory, an institution associated with United States Energy Department with great experience in managing atmospheric data; the initiative’s goal is to make knowledge generated with public funding accessible.

At an event organized by FAPESP and the UK’s Royal Society, researchers showed how partnerships are important in producing scientific results at the knowledge frontier.

Tool developed by a firm supported by FAPESP is being used to assess student learning in primary and secondary schools in the state of São Paulo.

In contrast with China and other countries where the disease spread slowly, in Brazil more than 300 people started the epidemic. Most were passengers flying in from Italy.

In animal testing, experimental Ebola vaccine based on platform developed by US pharmaceutical company in partnership with Brazilian researchers conferred immunity against hemorrhagic virus with single dose.

A formulation developed in Brazil is expected to protect against all 90-odd serotypes of the Streptococcus pneumoniae bacterium. Vaccines currently available in Brazil are effective against 13 serotypes at most.

The purpose of the agreement is to promote and deepen scientific and technological cooperation between researchers from São Paulo and the US Department of Energy’s high-energy physics laboratory.

Study by researchers at Brazil’s National Disaster Surveillance and Early Warning Center (CEMADEN) also shows a rise in the number of consecutive dry days, suggesting that extreme rainfall events are concentrated in shorter, more widely spaced periods.

As one of the Engineering Research Centers supported by FAPESP, the new center will focus on R&D for next-generation deep-sea oil production systems.

Techniques developed by researchers at the University of São Paulo with FAPESP’s support are helping to enhance the safety of health workers and enable scientists to understand more about the biology of the disease.

Researchers, small businesses and startups will receive BRL 30 million for projects to develop diagnostic kits, therapies and therapeutic procedures, ventilators, personal protective equipment for health workers and solutions for health services, among others.

Model developed by Brazilian researchers shows chaotic phase that placed objects in current orbits beginning within first 100 million years after formation of giant planets.

The study was conducted in Brazil and mapped the genes that are activated when mice resistant to Leishmania are infected. Molecules involved in the signaling pathway responsible for combating the parasite can serve as biomarkers for the evaluation of prognosis.

The aim of the initiative is to strengthen cooperation between the two countries in science, technology and innovation.

Brain4care has won FDA approval for use of its intracranial pressure sensor, developed and refined for 15 years, and plans to its build market share in the United States.

The viral therapy was tested in three elderly animals with spontaneous brain tumors by a group affiliated with the FAPESP-funded Human Genome and Stem Cell Research Center.

Made of chitosan, a natural polymer obtained from shellfish exoskeletons, the coating enhances mechanical strength, protects against microorganisms, and prevents mass loss due to evaporation. It can also be used to coat food packaging.

In a survey of 2,702 adolescents enrolled at schools in the city of São Paulo, 23% reported having been victims of violence in the previous year. Alcohol consumption, relationships with parents and friendships were the factors most closely associated with bullying and violence.

Research conducted in Brazil has developed an innovation that carries drugs directly to bacteria, with controlled release of the active component. The study is featured on the cover of Advanced Functional Materials.

An analysis performed with 264 people living in and around Campinas mapped 900,000 genetic markers distributed in their genomes. It aimed to lay the foundations for precision medicine and provide input for public health policy.

Using a novel technological platform, researchers at the University of São Paulo plan to produce a candidate vaccine against SARS-CoV-2 for testing in animals in the next few months.

Samples of the virus will be distributed to public and private clinical laboratories all over Brazil for use as positive controls. The goal is to enhance the labs’ capacity to perform diagnostic tests.

Perovskite, a class of crystalline material with potential applications in photovoltaic technology, is being studied by researchers affiliated with the Center for Innovation in New Energies (CINE), an Engineering Research Center supported by FAPESP.

The organizers will select 72 applicants, who can be undergraduates, graduates or postdoctoral researchers. Applications must be submitted by April 28.

Analysis of Atlantic Rainforest fragments shows how extinction of animal species, habitat loss and forest fragmentation affect networks of ecological interactions.

Brazilian scientific production in mathematics has a high impact and worldwide recognition. The knowledge created in the field must now be leveraged to fuel new businesses, innovations and job creation, according to the participants in a workshop co-organized by the Center for Mathematical Sciences Applied to Industry.

System developed by Brazilian startup with FAPESP’s support is being used in Rio de Janeiro on a pilot scale to detect problems in the operation of bus lines during rainstorms.

With FAPESP’s support, researchers at the University of São Paulo in Brazil and Oxford University in the UK trained the team at Adolfo Lutz Institute to use the methodology even before the virus arrived in Brazil. The genomic data will be useful for the development of vaccines and diagnostic tests.

Researchers in Brazil analyzed 12 types of tumor and established a gene expression profile associated with cachexia, a potentially fatal syndrome characterized by severe weight loss and muscle wasting.

Hosted by the University of São Paulo in Piracicaba (ESALQ-USP) in Piracicaba, SPARCBio (for short) will develop a new integrated pest management model to foster the sustainability of tropical agriculture. FAPESP and Koppert will invest BRL 40 million.

Researchers-based in São Paulo state and the Netherlands are collaborating on four projects that explore how restored forests function. The findings may be used as public policy inputs.

Experiments conducted in Brazil show that the positions of mouths and fins, among other variables, change according to foraging conditions during development.

Article by Brazilian researchers published in Biology of Reproduction reveals novel mechanisms involved in female gamete maturation.

The blood test method makes use of machine learning and can be used to predict whether patients will put on weight, unless they change their habits. The project was conducted in Brazil with funding from FAPESP.

Experiments with rats indicate that brain cells submitted to several forms of hypoxia underwent alterations to their energy production mechanism. Such condition may affect the fetus in pregnant women who have developed pre-eclampsia, a high blood pressure disorder.

World experts on this field of mathematics will assemble between July 28 and August 8 in Campinas, Brazil. The School is offering places for 100 undergraduate, graduate and postdoctoral students.

Brazilian researchers show that if 25% of a one-hectare forest remnant is cut down, the impact on the local climate will be a temperature increase of 1 °C. The study is published in PLOS ONE.

The imaging analysis system available at the University of São Paulo enhances the effectiveness of biological control of South American fruit flies based on the sterilization of males. The species mainly damages apple and peach orchards in the South Region of Brazil.

A discovery by scientists affiliated with a research center supported by FAPESP could contribute to the development of more powerful photosensitizers. When these molecules are exposed to light, they trigger biochemical processes that lead to the disruption of the cell membranes of tumors or pathogens.

Brazilian researchers found the level of uric acid in saliva to be a good indicator of body fat percentage. Study was designed to identify reliable biomarkers that can be used to develop quick noninvasive tests for early detection of chronic diseases.

Researchers are looking for partners to refine process that converts sugarcane bagasse and wheat straw into high-value compounds.

Pregnant women in situations of vulnerability will be assessed to study how alterations in gene expression caused by adverse childhood experiences influence brain development in their descendants. The ultimate goal is early prevention of mental health problems.