International Workshop on Metabolomics in the Context of Systems Biology

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Agência FAPESP* –Agência FAPESP – O BIOTA-FAPESP “International Workshop on Metabolomics in the Context of Systems Biology: a rational approach to search for lead molecules from nature” será realizado nos dias 25 e 26 de fevereiro de 2010, na sede da FAPESP, em São Paulo.
evento é isento de taxa de inscrição e as palestras terão tradução simultânea.


PROGRAM

February 25
      
8h00 - Registration

08h40 - Open Ceremony

Symposium I: Metabolomics and Systems biology as a tool for new drugs discovery   

9h00 - Systems Biology: a Gateway to Novel Discoveries - Robert Verpoorte, Leiden University, Holland 

9h50 - Integration of Structure and Ligands Based Drug Design Approaches for the Discovery of Lead Compounds from Natural Products - Adriano Andricopulo, USP, São Carlos, SP

10h15 - Inhibition of Photophosphorylation and Electron Transport Chain in Thylakoids by Natural Products - Maria Fátima das G. Fernandes da Silva, Ufscar, São Carlos, SP 
10h40 - The Development of New Products from Brazilian Biodiversity - Emerson Queiroz, Laboratório Aché, São Paulo, SP
11h05 - Coffee Break
11h20 - MS-based Metabolomic Approaches Combined with Microflow-NMR Methods for the Search of Original Stress Induced Biomarkers in Plants  - Jean-Luc Wolfender, Université de Genève
12h10 - Discussion
12h30 - Lunch Time (restaurants around FAPESP)
Symposium II: Plants and Associate Microorganisms as Potential source of New Biologically Active Molecules   

14h00 - Systems Biology of Symbiotic Bacteria and the Search for New Biologically Active Molecules- Jon Clardy, Harvard Medical School, USA

14h50 - Exploring Microbial Interactions in Natural Products Research- Monica Talarico Puppo, USP, Ribeirão Preto, SP

15h15 - Search for Potential Antitumoral, Antioxidant, Anti-inflammatory, Antifungal, Antidiabetic, Acetylcholinesterase and Myeloperoxidase Inhibitory Natural Compounds from Cerrado and Atlantic Forest - Dulce Helena Siqueira Silva, UNESP, Araraquara, SP
15h40 - Coffee Break
16h00 - Footprinting of the ‘Final-fate Compounds’ in Systems Biology: Reading the Nature’s Message- Mario Palma, Unesp, Rio Claro, SP
16h25 - Molecular diversity among basal Angiosperms - Massuo Jorge Kato, USP, São Paulo, SP
16h50 - Cultured Cyanobacteria: A Promising Source for Novel Bioactive Natural Products - Jimmy Orjala, University of Illinois at Chicago, USA
17h40 - Discussion



February 26
      
Symposium III: New Advance Methodology for the Search Drug Discovery    

9h00 - New Advance Methodology for the Search Drug Discovery- Arthur Edison, University of Florida, USA

9h50 - ESI-MS/MS Techniques and Applications for the Analysis of Natural Products- Norberto Peporine Lopes, USP, Ribeirão Preto,SP

10h15 - Search to be applied in enantioselective oxidation of secondary alcohols and bioreduction of ketones - Leandro Helgueira Andrade, USP, São Paulo, SP
10h40 - Novel application of 2D and 3D-similarity searches to assess compound selectivity among Cytochrome P450 2C9, 2D6 and 3A4 substrates - Carlos Alberto Montanari, USP, São Carlos, SP
11h05 - Coffee Break
11h30 - Innovative Strategies to Enhance Structural Diversity of Natural Products and Discovery of their New Uses  - A. A. Leslie Gunatilaka, The University of Arizona, USA
12h20 - Discussion
12h40 - Lunch Time (restaurants around FAPESP)
Symposium IV: New Approach to Screening Biodiversity Source Materials and New Trends in Pharmacology and Toxicology to Select New Targets   

14h00 - Taxol, Tubulin and Tumors: Challenges in the New Era of Cancer Therapeutics- Suzan Band Horwitz, Albert Einstein College of Medicine, USA

14h50 - Signaling through acetylcholine: multiple targets, phylogenetic conser- vation, and rich pharmacology- Newton G. Castro, UFRJ, Rio de Janeiro

15h20 - Decoding the Signaling Network in Malaria Parasites - Célia Regina Silva Garcia, USP, São Paulo, SP
15h50- Recent Studies of Natural Products Isolated from Brazilian Plants: Evaluation of Antigenotoxicity, Antimutagenicity and Antitumoral Assays - Christiane Pienna Soares, Unesp, Araraquara, SP
16h15 - Coffee break
16h30 - Novel Heparinomimetics with Potential Therapeutic Use in Cardiovascular and Inflammatory Disorders - Helena B. Nader, UNIFESP, SP
17h00 - Discussion
Close Remarks

17h30 - Vanderlan da Silva Bolzani, Unesp, Araraquara, SP


FAPESP: Rua Pio XI, 1500 – Alto da Lapa - São Paulo – SP
Sugestão de estacionamento: Taticar, R. Jorge Americano, 89


    Clique para inscrever-se 

Mais informações: (11) 3838-4006/3838-4216 - marina@fapesp.br

<p><b>Agência FAPESP</b> – O BIOTA-FAPESP “International Workshop on Metabolomics in the Context of Systems Biology: a rational approach to search for lead molecules from nature” será realizado nos dias 25 e 26 de fevereiro de 2010, na sede da FAPESP, em São Paulo.</p>
<p>evento é isento de taxa de inscrição e as palestras terão tradução simultânea.<br />
<br />
<br />
<b>PROGRAM<br />
</b><br />
<b>February 25</b><br />
      <br />
8h00 - <b>Registration</b><br />
<br />
08h40 - <b>Open Ceremony</b><br />
<br />
<b>Symposium I: Metabolomics and Systems biology as a tool for new drugs discovery </b>  <br />
<br />
9h00 - <b>Systems Biology: a Gateway to Novel Discoveries </b>- Robert Verpoorte, Leiden University, Holland <br />
<br />
9h50 - <b>Integration of Structure and Ligands Based Drug Design Approaches for the Discovery of Lead Compounds from Natural Products </b>- Adriano Andricopulo, USP, São Carlos, SP<br />
<br />
10h15 - <b>Inhibition of Photophosphorylation and Electron Transport Chain in Thylakoids by Natural Products</b> - Maria Fátima das G. Fernandes da Silva, Ufscar, São Carlos, SP </p>
<p>10h40 - <b>The Development of New Products from Brazilian Biodiversity</b> - Emerson Queiroz, Laboratório Aché, São Paulo, SP</p>
<p>11h05 - <b>Coffee Break</b></p>
<p>11h20 - <b>MS-based Metabolomic Approaches Combined with Microflow-NMR Methods for the Search of Original Stress Induced Biomarkers in Plants </b> - Jean-Luc Wolfender, Université de Genève</p>
<p>12h10 - <b>Discussion</b></p>
<p>12h30 - <b>Lunch Time (restaurants around FAPESP)</b></p>
<p><b>Symposium II: Plants and Associate Microorganisms as Potential source of New Biologically Active Molecules </b>  <br />
<br />
14h00 - <b>Systems Biology of Symbiotic Bacteria and the Search for New Biologically Active Molecules</b>- Jon Clardy, Harvard Medical School, USA<br />
<br />
14h50 - <b>Exploring Microbial Interactions in Natural Products Research</b>- Monica Talarico Puppo, USP, Ribeirão Preto, SP<br />
<br />
15h15 - <b>Search for Potential Antitumoral, Antioxidant, Anti-inflammatory, Antifungal, Antidiabetic, Acetylcholinesterase and Myeloperoxidase Inhibitory Natural Compounds from Cerrado and Atlantic Forest</b> - Dulce Helena Siqueira Silva, UNESP, Araraquara, SP</p>
<p>15h40 - <b>Coffee Break</b></p>
<p>16h00 - <b>Footprinting of the ‘Final-fate Compounds’ in Systems Biology: Reading the Nature’s Message</b>- Mario Palma, Unesp, Rio Claro, SP</p>
<p>16h25 - <b>Molecular diversity among basal Angiosperms</b> - Massuo Jorge Kato, USP, São Paulo, SP</p>
<p>16h50 - <b>Cultured Cyanobacteria: A Promising Source for Novel Bioactive Natural Products</b> - Jimmy Orjala, University of Illinois at Chicago, USA</p>
<p>17h40 - <b>Discussion<br />
<br />
<br />
</b></p>
<p><b>February 26</b><br />
      <br />
<b>Symposium III: New Advance Methodology for the Search Drug Discovery  </b>  <br />
<br />
9h00 - <b>New Advance Methodology for the Search Drug Discovery</b>- Arthur Edison, University of Florida, USA<br />
<br />
9h50 - <b>ESI-MS/MS Techniques and Applications for the Analysis of Natural Products</b>- Norberto Peporine Lopes, USP, Ribeirão Preto,SP<br />
<br />
10h15 - <b>Search to be applied in enantioselective oxidation of secondary alcohols and bioreduction of ketones</b> - Leandro Helgueira Andrade, USP, São Paulo, SP</p>
<p>10h40 - <b>Novel application of 2D and 3D-similarity searches to assess compound selectivity among Cytochrome P450 2C9, 2D6 and 3A4 substrates</b> - Carlos Alberto Montanari, USP, São Carlos, SP</p>
<p>11h05 - <b>Coffee Break</b></p>
<p>11h30 - <b>Innovative Strategies to Enhance Structural Diversity of Natural Products and Discovery of their New Uses </b> - A. A. Leslie Gunatilaka, The University of Arizona, USA</p>
<p>12h20 - <b>Discussion</b></p>
<p>12h40 - <b>Lunch Time (restaurants around FAPESP)</b></p>
<p><b>Symposium IV: New Approach to Screening Biodiversity Source Materials and New Trends in Pharmacology and Toxicology to Select New Targets </b>  <br />
<br />
14h00 - <b>Taxol, Tubulin and Tumors: Challenges in the New Era of Cancer Therapeutics</b>- Suzan Band Horwitz, Albert Einstein College of Medicine, USA<br />
<br />
14h50 - <b>Signaling through acetylcholine: multiple targets, phylogenetic conser- vation, and rich pharmacology</b>- Newton G. Castro, UFRJ, Rio de Janeiro<br />
<br />
15h20 - <b>Decoding the Signaling Network in Malaria Parasites</b> - Célia Regina Silva Garcia, USP, São Paulo, SP</p>
<p>15h50- <b>Recent Studies of Natural Products Isolated from Brazilian Plants: Evaluation of Antigenotoxicity, Antimutagenicity and Antitumoral Assays</b> - Christiane Pienna Soares, Unesp, Araraquara, SP</p>
<p>16h15 - <b>Coffee break</b></p>
<p>16h30 - <b>Novel Heparinomimetics with Potential Therapeutic Use in Cardiovascular and Inflammatory Disorders</b> - Helena B. Nader, UNIFESP, SP</p>
<p>17h00 - <b>Discussion</b></p>
<p><b>Close Remarks<br />
<br />
</b>17h30 - Vanderlan da Silva Bolzani, Unesp, Araraquara, SP<br />
<br />
<b><br />
FAPESP:</b> Rua Pio XI, 1500 – Alto da Lapa - São Paulo – SP<br />
Sugestão de estacionamento: Taticar, R. Jorge Americano, 89<a href="http://www.fapesp.br/biota_metabolomics/"><b><br />
</b></a></p>
<ul>
    <li><a href="http://www.fapesp.br/biota_metabolomics/"><b>Clique para inscrever-se </b></a></li>
</ul>
<p>Mais informações: (11) 3838-4006/3838-4216 - <a href="mailto:marina@fapesp.br"><b>marina@fapesp.br</b></a><br />
 </p>