Non-invasive method uses samples of saliva or other body fluids. The diagnosis can be obtained by means of computational techniques for visualizing data and machine learning.
Researchers compared data for pregnant women in Rio de Janeiro and Manaus who were infected by zika virus in 2015-16. Factors that influenced the risk of fetal malformation were the high zika attack rate in the area and being infected in the first trimester of pregnancy.
A project led by researchers at Getúlio Vargas Foundation in Brazil and the University of Michigan in the US produced a detailed analysis of the effects of public policies and government decisions on the response to COVID-19, highlighting the factors that influenced its success or failure in many countries and regions around the world.
Research by a student at the University of São Paulo examines embassies sent to Brazil by the African kingdom in the period 1795-1805. Their purpose was to build closer ties with the Portuguese authorities and Brazilian slave buyers.
The study could have applications in spintronics and quantum computing. It was conducted by an international collaboration and published in Nature. Its first author is a researcher at the University of São Paulo.
The study was conducted in the city of São Paulo, with over 2,000 participants who were active or retired staff of the University of São Paulo and enrolled in the Brazilian Longitudinal Study of Adult Health (ELSA-Brazil). The researchers say the city has one of the highest prevalence rates of psychiatric disorders in the world.
Celso Lafer, a former Brazilian foreign minister and ex-president of FAPESP, delivered the first FAPESP 60 Years Lecture. The online event also featured Patrícia Ellen, São Paulo State Secretary for Economic Development.
A study conducted at the University of São Paulo suggests that tissues specializing in saliva production and secretion serve as reservoirs for SARS-CoV-2, magnifying its infectious potential.
According to a recently published study, when newborns observe adults performing everyday tasks, their social, motor and cognitive development is stimulated.
One of the technologies developed has RT-PCR-like precision and can analyze many patient samples simultaneously using a platform available in all Brazilian laboratories. A research group at the Federal University of São Carlos has also created a portable rapid test that detects the viral antigen in saliva and does not require a nasal swab.
Diabetics exert less force to hold an object than people with other diseases that affect the nervous system. Grip force is a key behavioral biomarker to detect incipient diabetic neuropathy.
The case of persistent infection was documented by researchers at the University of São Paulo, involving an immunocompromised patient in his forties. Several mutations were detected by whole-genome sequencing of the virus in samples collected during a seven-month period.
Butantan Institute produces CoronaVac and is testing two new vaccines. Four projects are under way at the University of São Paulo, and two at startups supported by FAPESP’s PIPE innovation funding program.
Simulations run by Brazilian scientists on a supercomputer at the National Space Research Institute (INPE) show that the direct impact of rising levels of carbon dioxide over the Amazon rainforest would be a reduction in rainfall equivalent to or even greater than the impact of complete substitution of the forest by pasture. The result calls attention to the need for regional and global action to mitigate the adverse effects of climate change.
In an online seminar organized by FAPESP, researchers in Brazil and the United States presented preliminary results of studies on mental health and quality of life among survivors of COVID-19 up to six months after discharge from hospital.
Tests performed by Brazilian researchers after the first 16 weeks of COVID-19-induced confinement showed loss of muscle strength and diminished aerobic capacity, as well as an increase in cholesterol and glycated hemoglobin, both of which are risk factors for metabolic disorders.
Contradicting theories of primatologists, a study led by Brazilian scientists shows that in a habitat with high hunting pressure, the risk of predation influences the habits of these monkeys more than the availability of food. They spend less time in areas they perceive as ‘more dangerous’ even if plant biomass and invertebrates are more abundant there.
Researchers have completed the first stage of a technical study on the creation of environments designed to foster the development of innovative solutions and creativity in the cities of São Paulo and Campinas.
In the run-up to the 26th UN Climate Change Conference of the Parties (COP26), experts participating in a webinar hosted by FAPESP showed that the 2020 revision of Brazil’s nationally determined contribution failed to improve targets and allows in practice for a higher level of greenhouse gas emissions.
A solution developed by a startup based in São Paulo state combines fungicidal action and delayed ripening. The researchers who founded the startup took part in the 17th edition of the PIPE High-Tech Entrepreneurial Training Program.
A study conducted at São Paulo State University shows that mathematical models used to describe the physical behavior of magnetic materials can also be used to describe the spread of the disease.
The phenomenon is linked to gradual contraction of the tropical rain belt over the last 5,000 years, according to a study conducted at the University of São Paulo. Its findings can help predict the region’s future climate.
The presence of Candida auris in a hospital in Salvador, Bahia, was confirmed at end-2020 and reported in an article in the Journal of Fungi. The fungus can cause a lethal invasive disease and is ringing alarm bells because of the speed with which it develops drug resistance.
Brazilian researchers show that a combination of inflammatory cytokines in the blood and cannabis use, daily or during adolescence, heightens the odds of developing psychiatric disorders.
Fewer Atlantic mangrove fiddler crab embryos survived in a warmer, more acid environment mimicking conditions forecast for the end of this century. Given the important ecological role of this invertebrate in mangroves, the researchers warn of a potential cascade effect.
Researchers at the University of São Paulo discover that the fungus Fusarium verticillioides uses volatile compounds to manipulate insects and plants, promoting its own dissemination.
The system, developed by a startup supported by FAPESP, in partnership with researchers at the University of Campinas, helps plantation managers choose the optimal time to harvest the crop.
Researchers at the University of São Paulo conducted experiments with blood plasma from 60 volunteers infected in 2020 by SARS-CoV-2 lineage B.1.1.28. In 84% of cases, antibodies in the samples neutralized the Gamma variant in cultured cells.
Supported by FAPESP and led by a researcher at the Federal University of São Paulo, EPICOVID-19 BR 2 tested 120,000 people in 133 cities between January 25 and April 24, 2021. Amazonas was the state with the highest seroprevalence, with positive test results accounting for 31.4%. The nationwide average was 15%.
The discovery, made possible by a partnership between a research group and a startup in São Paulo state (Brazil), could lead to novel treatments for intracranial hypertension and its complications, such as stroke.
A group at the University of Campinas used protein mapping to show how abnormal levels of the neurotransmitter glutamate impair the functioning of neurons and oligodendrocytes. The findings could serve as a basis for more effective treatment.
The device was used for the first time to culture two maternal endometrial cell types, revealing the effects of alterations in glucose and insulin levels in the uterine environment. It can also be converted into a model for study of pregnancy in humans and endometriosis.
Researchers describe how fumiquinazoline C is synthesized and investigate its function in conidia, asexual non-motile spores of the fungus Aspergillus fumigatus that can cause severe infections in immunosuppressed patients. The discovery could lead to the development of novel medications.
Illegal logging to clear land for cattle grazing has fueled growth in Brazil’s greenhouse gas emissions, according to participants in a webinar on the prospects for COP26 hosted by FAPESP.
The largest series of autopsies ever performed on children who died from COVID-19 showed that the ability of the novel coronavirus to invade and damage the tissue of all major organs is one of the factors leading to multisystem inflammatory syndrome in children (MIS-C).
Hybrid material made from magnetite nanoparticles sticks to contaminants and can be removed from water by a magnet. The technique can be adapted for use in removing synthetic dyes, drugs, hormones and pesticides.
Models for professional use were the most effective at retaining aerosol particles of a size equivalent to the novel coronavirus, followed by TNT masks sold in drugstores. The efficacy of fabric masks ranged from 15% to 70%. A tight fit and lack of seams enhanced protection.
Patients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80, according to a study by Brazilian researchers.
Cities located in metropolitan areas of this Brazilian state score better according to an index that measures the existence of public policies designed to adjust critical sectors to the impacts of climate change.
The study shows that the 2019-20 drought resulted from a natural meteorological phenomenon similar to the one that caused the 2014-16 critical water shortage in São Paulo state, Southeast Brazil.
The call aims to advance knowledge of the societal effects of the COVID-19 pandemic and solutions to mitigate them. The submission deadline is July 12. Eligibility checking ends June 14.
A research group at São Paulo State University (UNESP) analyzed how Candida albicans fungi and Staphylococcus aureus bacteria influence gene expression and tumor cell survival.
The study was conducted in a Brazilian national park and was based on analysis of tree rings in the species Amburana cearensis, as well as satellite images.
With support from FAPESP via its program to fund innovative research, the startup has developed a rejuvenating serum based on bioactives obtained from sweet wormwood, a plant used in traditional Chinese medicine.