Potential targets for anti-malarial drugs and for preventing transmission of the parasite are described in articles in Genes & Cancer and Nature Communications.
Symposium on drug discovery aims to disseminate culture of innovation and explore ways to facilitate conversion of basic research into drugs and other innovative products.
Researchers performed in vitro trials to test the effect of L-asparaginase on acute lymphoblastic leukemia cells and published the results in Scientific Reports.
Project selected in a coordinated call for proposals involves research groups from five Brazilian states and six large corporations, as well as European groups.
Lack of transparency in the setting of prices paid to agricultural producers can have negative effects on investment in sugarcane and orange growing and processing industries.
Researchers affiliated with GOAmazon and the Large Scale Biosphere-Atmosphere Experiment in Amazonia presented the findings of projects conducted in recent years and discussed priorities for 2017-21
In a presentation at FAPESP, German researcher Frank Allgöwer spoke about how cybernetic engineering and human sciences can contribute to a better understanding and control of complex dynamic systems in the future
Limited funds and technical capacity make smaller towns more vulnerable to environmental disasters, whereas scale is the main challenge for large cities.
Studies in mice suggest that two drugs capable of inhibiting the enzyme TrxR-1 – already available commercially for other purposes – reduce inflammation and mortality in patients with sepsis.
An article in Blood shows that administering the anti-hypertensive drug amlodipine in conjunction with conventional chelation therapy helps combat health problems caused by the buildup of iron in organs.
Researchers in the Brazilian states of São Paulo, Amazonas and Pará have demonstrated that extracts from this native plant are rich in gallic acid, which inhibits the action of enzymes that degrade collagen.
A complete database of Tribe Bignonieae, which consists mainly of lianas, contains information on genetics, taxonomy, morphology, geography and evolution.
Projects selected through this joint call for proposals will develop novel routes for the production of biofuels from non-conventional feedstocks, as well as high-value chemicals.
In 1990-2000 the Polar Front shifted southward twice as much as in the previous 900 years, potentially altering ocean temperatures and ecosystem functions.
In studies with tumor stem cells, researchers at Uruguay's University of the Republic have identified regulators with the potential to interfere in the development of cancer cells.
Researchers evaluated the application of a computer model for hydrological disaster prediction and early warning in the Doce river basin, which contains more than 200 Brazilian municipalities.