A cross-border team of researchers refute arguments that carbon debt, opportunity cost and indirect land-use change prevent greenhouse gas mitigation by biofuels.
Scientists at a research center supported by FAPESP identified a non-inherited mutation in blood cells from a patient with GATA2 deficiency that may have prevented bone marrow failure and other clinical manifestations.
Preliminary results of patient tissue analysis show that the virus infects adipocytes and alters the quantity of signaling molecules released by these cells into the bloodstream.
Analysis of DNA from 1,171 over-sixties living in São Paulo will enable scientists to identify genetic mutations responsible for diseases or important to healthy aging, according to the authors of the study.
Group led by Brazilian ecologist shows defaunation wiped out 40% of the ecosystem services provided or supported by mammals, such as ecotourism, disease control and soil formation. Large-bodied mammals are disappearing fastest.
Model developed by startup supported by FAPESP enables scientists to assess efficacy and safety of sunscreens and anti-aging products under conditions closely resembling real life.
Incentives to drive a rapid recovery by the sector, one of the hardest hit by the COVID-19 pandemic, will contribute to a resumption of world economic growth, save or create millions of jobs, and contain global emissions of carbon dioxide, experts say.
Monoclonal antibody tested by researchers at University of São Paulo and experimental drug given to patients in Italy by University of Pennsylvania research group promoted rapid improvement of respiratory function in patients hospitalized in severe condition.
Investigation conducted by international group of researchers showed that chikungunya virus can cause neurological infections. Risk of death in subacute phase is higher for patients with diabetes and significant for young adults.
Three waves of the disease swept the state between 2016 and 2018. An international group of researchers described how the virus spread in a study published in PLOS Pathogens based on the sequencing of 51 viral isolates extracted from mosquitoes and monkeys.
Intervention was tested in mice by Brazilian researchers. Study showed that targeted stimulation of PKA production promoted muscle growth and enhanced resistance to fatigue.
Sirius’s protein crystallography beamline analyzed more than 200 protein crystals from the novel coronavirus as they were exposed to tiny fragments of widely used drugs. If a compound fits perfectly into a target protein, its action can be blocked in the virus.
Brazilian researchers discovered that sTREM-1 protein in immunoglobulin family could be a very useful biomarker to help medical teams make clinical decisions.
Findings reported by Brazilian researchers in PLOS Neglected Tropical Diseases help explain why only some babies whose mothers are infected during pregnancy are born with microcephaly and other anomalies.
Adaptation of muscle tissue to aerobic exercise alters the metabolism of muscle stem cells, helping them recover from injury. Findings may contribute to treatment of cachexia, sarcopenia and other conditions associated with lean mass loss.
Renowned scientists will address topics related to how society has been coping with this threatening environment and will discuss factors that influence behavioral change.
Analysis identified 525 genes encoding proteins that act on the nervous system, cardiovascular system and cell walls. One of the molecules proved effective against cancer cells in preliminary test results.
The newest Engineering Research Center will initially focus on challenges relating to health, the environment, food production chains, the future of work, and the development of natural language processing tools for Brazilian Portuguese.
Analyses by Brazilian researchers suggest alterations to pH caused by stomach acid lead to increase in expression of ACE2 and make cells more susceptible to infection by novel coronavirus.
Experiments conducted by Brazilian researchers with lymphocytes isolated from COVID-19 patients showed the virus using the protein CD4 to invade cells that play a key role in coordinating the immune response.
In an article published in the Journal of Experimental Medicine, a group affiliated with a FAPESP-supported research center reports that an enzyme associated with energy production in cells also participates in the differentiation of immune cells involved in exacerbated inflammation. The discovery could lead to more effective treatment.
Study by Brazilian and South African researchers is the first to prove, using a graph analysis tool, that REM dream narratives tend to be more complex and connected than reports of non-REM dreams
Led by research groups from the universities of Campinas and São Paulo, the investigation combined MRI scans of mild COVID-19 patients, analysis of brain tissue samples from patients who died from COVID-19, and experiments performed with human nerve cells infected in the laboratory.
Brazilian startup Agrobee signs agreement with Agroven, an investment club run by family farmers who want to promote technological development in the sector.
A study quantified the size and age of the forests that grow naturally in degraded and abandoned areas, creating 131 benchmark maps for Brazil. The Amazon has the most restored forests and the Atlantic Rainforest biome has the oldest.
Brazilian researchers found the novel coronavirus replicating inside immune cells from patients hospitalized with COVID-19. Experiments on lymphocytes infected in the laboratory showed that viral entry induced programmed cell death.