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Discovery of a new viral evasion mechanism, and of a monoclonal antibody that subverts it, is an advance in immunotherapy offering the prospect of effective host-directed treatment to combat infections.

Researchers at the University of São Paulo conducted in vitro experiments with bone cells to confirm the properties of the novel biomaterial. Their findings suggest it can replace natural bone in grafting procedures to remedy defects or injuries.

A study comparing solutions developed in São Paulo and Melbourne, Australia, highlights the huge potential for expansion in the Brazilian megacity.

Researchers from the Butantan Institute and collaborators reveal why recombinant BCG induces a stronger and longer-lasting response than the conventional vaccine.

A Brazilian study assessed 237 patients treated at the University of São Paulo’s general and teaching hospital. The researchers found that 92% still had lung damage two years after discharge, with fibrosis (33% of cases) arousing most concern.

According to the authors of the study, infection by one virus was expected to afford protection against the other, preventing co-circulation. They warn of the risk of transmission of Mayaro in urban areas owing to deforestation and advocate more effective epidemiological surveillance.

Brazil is considered “one of 12 countries that produce the most science” by the French government. The purpose of the event was to explore opportunities for funding joint research projects.

In an article published in Nature Medicine, a group at the State University of Campinas stresses that Yanomami children are suffering the most severe nutritional deficit of any Indigenous community in the Americas and warns of long-term consequences for health.

A study shows that ritual dances and other displays in which workers select future queens with optimal reproductive capacity are found among all representatives of this group of wasps.

About BRL 130 million will be invested in the new centers, which will develop solutions to challenges posed by the São Paulo State Government.

By analyzing samples from obese non-diabetics, researchers from the State University of Campinas found that high blood levels of saturated fatty acids cause pre-activation of innate immune cells that, when infected with SARS-CoV-2, produce elevated levels of inflammatory molecules. Results were presented during FAPESP Week China.

Participants emphasized their desire to strengthen scientific and technological cooperation between Brazil and China and celebrated the friendly relations between the two countries.

Companies are currently involved in 15% of the collaborative research projects conducted by scientists in São Paulo state and Italy, according to data presented at an event hosted by FAPESP.

At the meeting, leaders of the two institutions shared experiences on removing red tape and discussed the use of AI to assess project proposals, as well as preparations for FAPESP Week Berlin in 2025.

The award was presented to the President of FAPESP by Emmanuel Lenain, France’s ambassador to Brazil.

Located in Botucatu, the plant will perform outsourced medical drug development and production services for pharmaceutical companies, biotechs and other research institutions, complying with best manufacturing practices.

Startups were selected to participate in FAPESP Week through a call for proposals from the Innovative Research in Small Businesses Program, launched in April; the focus on innovation should be maintained in future editions of the event.

In a study conducted by Brazilian researchers, blood levels of an amino acid called homocysteine correlated with the development of a disease that affects a third of the inhabitants of São Paulo city.

In a study conducted at the University of São Paulo and described in Scientific Reports, the diameter of semiconductor quantum dots was monitored in real time via the wavelength of the emitted light.

Innovation stems from a project on gas turbines conducted at the Engineering School and could make the use of CPAP more comfortable.

The aim is to extend and diversify the sources of funding for deep techs supported by the Innovative Research in Small Business Program.

Supported by FAPESP, Shell, the Technological Research Institute (IPT) and the University of São Paulo (USP), this Applied Research Center will investigate technologies that promote decarbonization and optimization of deep-sea oil and gas operations, contributing to the future of the offshore industry.

The study is the first to show that femtosecond pulsed laser irradiation is effective and safe in mice with induced ocular melanoma, paving the way for minimally invasive targeted treatment of the disease in future.

Researchers analyzed landslides caused by storms in São Sebastião (Brazil) in 2023, when at least 65 people died, and suggest involvement of the local community in contingency programs.

In an online seminar hosted by FAPESP and the U.S. National Science Foundation, researchers presented on initiatives aimed at promoting equity in science, technology, engineering and mathematics (STEM).

The process, developed by Brazilian and Spanish scientists, obtains anthocyanin from fruit processing waste with a higher yield than the usual method.

Heads of the two agencies met on June 24th and renewed the cooperation agreement signed in 2019; a joint workshop on precision agriculture will be held on Saturday as part of FAPESP Week China.

As described in Scientific Reports, the study involved analysis of blood samples from volunteers infected by Plasmodium vivax, which produces forms that lie dormant in the host and can be reactivated months after treatment. The findings will help detect and diagnose these forms, with significant potential to enhance control and treatment of the disease in future.

In vitro tests show that some of the materials are toxic in high concentrations and can cause inflammatory processes.

Developed by researchers at the University of São Paulo in Brazil, the system used the port city of Santos as a sample space, and could enhance the efficiency of civil defense activities in the context of extreme weather events.