Experiments involving mice and conducted by Brazilian researchers showed four weeks of training with weights to be sufficient to reverse behavioral and physical alterations characteristic of the disease.
Trials involving mammalian cells were conducted by researchers in São Paulo state, Brazil. Although it endangers biodiversity along much of the coast, sun coral could be an ally in combating Chagas disease, which affects 7 million people worldwide and lacks effective treatment.
The discovery was made by researchers affiliated with institutions in Brazil and Chile. Their analysis of oral cells that expressed human papillomavirus proteins and were exposed to cigarette smoke pointed to an increase in levels of an enzyme associated with tumor progression and DNA damage.
The study by Brazilian researchers showed that the microscopic arachnids rid stingless bee colonies of excessive fungi and serve as food for the larvae of these honey-making insects.
Contrary to the predominant view held since the eighteenth century, the French philosopher and physician saw the organism as a totality interacting with its environment rather than a mere aggregation of parts whose functioning depended only on the right amount of organic substances.
A novel methodology used in the 24th edition of the PIPE High-Tech Entrepreneurial Training Program will guide 21 innovative startups in the process of developing customers and refining their business models, among other competencies.
Scientists analyzed data for the period from 232 Indigenous Territories in Brazil. Results published in Scientific Reports show deforestation rates accelerating between 2019 and 2021.
A study of 40 asymptomatic subjects living with HIV conducted at São Paulo State University showed that a daily dose of 500 mg was safe and helped combat premature aging.
Brazilian researchers analyzed data from MRI scans and various tests to detect biological alterations linked to the neurological symptoms most reported by patients, especially anxiety, depression, sleepiness and fatigue. The latest results were presented to the ninth edition of BRAINN Congress.
Soon to be officially launched, IPOS is a coalition of 16 research institutions, research funders and universities. Its mission will be to bridge the science-policy divide and help protect the world’s ocean environment.
Scientists at the University of São Paulo have shown that the occurrence of mesoscale convective systems, which account for 40% of precipitation in the Amazon, is already being affected by climate change.
Bone cavities called air sacs appeared in the ancestors of long-necked dinosaurs about 225 million years ago, according to the analysis of a specimen found in Rio Grande do Sul state, South Brazil. The study also shows that air sacs did not evolve as linearly as scientists believe.
The technique was developed at the Federal University of São Carlos (UFSCar) in São Paulo state, Brazil, and could impact the manufacturing of batteries, smartphone screens and other devices.
Carapace resembling scaled armor used by medieval knights appears to be first evidence of defense against predators and linked to origin of large group of animals with bilateral symmetry, which includes humans. Advanced techniques including electron microscopy and tomography applied to rocks found in Brazil in the 1970s enabled scientists to reconstruct this animal’s morphology.
The data, referring to Brazil, Argentina, Colombia and Guatemala, was presented by the FAPESP Bioenergy Research Program (BIOEN) during a seminar hosted by the International Energy Agency.
The study combined models that predict urban expansion and land-use changes with hydrodynamic models, and the results were validated using actual data for São Caetano do Sul, a city in metropolitan São Paulo.
A research group at Butantan Institute performed tests on animal models with asthma as a reference and demonstrated that the peptide from Thalassophryne nattereri, common in North and Northeast Brazil, is safe and efficacious.
The alert came from scientists who participated in the 10th German-Brazilian Dialogue on Science, Research and Innovation, organized by the German Center for Science and Innovation in São Paulo in partnership with FAPESP.
Esper Kallás, who heads Latin America’s leading producer of vaccines, delivered the Second 2023 FAPESP Lecture on “Viruses, pandemics and vaccines”. He spoke about the “100 Day Mission” to produce novel vaccines in just over three months.
Brazilian technology developed with FAPESP’s support can be used to spray large or small areas, economizing inputs, lowering costs and mitigating environmental impacts.
The call was issued in 2022 by the Global Alliance for Chronic Diseases, a transnational consortium of research funders set up to combat chronic non-communicable diseases in low- and middle-income countries. Two proposals supported by FAPESP were among those approved.
Representatives from 81 research funding agencies from 63 countries are meeting this week in The Hague, in the Netherlands, for the Annual Meeting of the Global Research Council, co-organized by FAPESP. In discussion, topics that will help shape the future of research around the world.
A charter of principles was ratified during the annual meeting of the Global Research Council. The goal is to establish common practices to assess the quality of the science produced and facilitate international collaborations.
Assessment was made by experts at the third day of the Annual Meeting of the Global Research Council. During the event, practices on funding research on the topic were ratified by representatives of funding agencies from 63 countries.
This assessment was made by participants of an event promoted on Tuesday by the Gender Working Group of the Global Research Council. One of the panelists was Marco Antonio Zago, president of FAPESP.
Initiatives developed by Elsevier, Royal Society of Chemistry, South Africa’s National Research Foundation and German Research Foundation were presented at event held in The Hague, Netherlands.
Discovered by Uruguayan scientists in 2013, two psychrophilic (cold-adapted) species have been experimented with since 2018 by a partnership between IIBCE in Montevideo and the University of São Paulo in Brazil.
Study mapped knowledge of nature-based solutions among municipal staff responsible for projects in 20 Brazilian cities. The survey points to the need to adapt the approach used in the northern hemisphere to local conditions.
Researchers in São Paulo state analyzed data for over 1 million patients hospitalized for treatment by the public health service after contracting COVID-19. Lower levels of inflammatory cytokines and fewer ACE2 receptors for the virus to bind to may be the explanation.
In experiments involving rats, researchers at São Paulo State University found that periods of low oxygen levels in the first months of life can lead to dysregulation of the sympathetic autonomic nervous system, which controls functions such as heart rate and blood pressure. The discovery points to possible routes to the development of novel therapies.
A biodressing containing human umbilical cord stem cells was produced in a 3D printer by the startup In Situ Cell Therapy. Researchers at the University of São Paulo found that when used on diabetic mice, the “smart” biodressing modulated the immune response, stimulated collagen synthesis and enhanced tissue repair.
Research groups in São Paulo state and Mozambique analyzed carotenoids in over 1,000 sweet potatoes and found some with 88% more beta-carotene, a precursor of vitamin A.
Described by Benjamin Franklin in the mid-eighteenth century, the kite experiment was an important step toward our modern understanding of electricity, but the pictures that popularized this episode are full of inaccuracies.
Leishmania alters the structure of the human protein that would normally induce the death of infected cells and weakens the inflammatory response. Reported in Nature Communications, the discovery could serve as a basis for better treatment.
No fewer than eight important hydrographic basins depend on the ecosystems that make up the Cerrado, Brazil’s savanna-like biome, but ambiguities in the legislation have permitted the advance of soybean plantations in the region. The warning is in an article by Brazilian researchers in the journal Perspectives in Ecology and Conservation.
A study by researchers at the State University of Campinas showed that although the two types of training produce similar metabolic stress, muscle activation is different.
An analysis conducted at the University of São Paulo showed that no sample exceeded the recommended limit for aflatoxin M1, a contaminant of fungal origin considered carcinogenic. Nevertheless, the researchers warn of the need to demand best practices in dairy production.
A program developed by researchers at the University of São Paulo included three weekly sessions of up to 80 minutes each for 16 weeks, with positive effects on cardiorespiratory fitness, lung function, functional capacity, body composition and persistent symptoms.