Researchers at Butantan Institute succeeded in reducing the toxicity and potentiating the analgesic effect of crotoxin by encapsulating it in nanostructured silica. The results of tests in an animal model of neuropathic pain, one of the hardest kinds of pain to treat, are promising.
This topic was discussed by specialists from several countries at the São Paulo School of Advanced Science on Mental Health and Evidence-Based Interventions, an event held with the support of FAPESP.
Brazilian researchers found the level of uric acid in saliva to be a good indicator of body fat percentage. Study was designed to identify reliable biomarkers that can be used to develop quick noninvasive tests for early detection of chronic diseases.
Pregnant women in situations of vulnerability will be assessed to study how alterations in gene expression caused by adverse childhood experiences influence brain development in their descendants. The ultimate goal is early prevention of mental health problems.
Undergraduate, graduate students and postdoctoral fellows from all countries can apply by February 22. One hundred vacancies are offered, half of which are for international students.
Researchers at the University of São Paulo find that a rise of 1.1 °C in the average temperature in Southeast Brazil between 1955 and 2004 correlates mainly with a rise in greenhouse gas levels due to human activities.
Thanks to the use of high-resolution microcomputed tomography, a cross-border research collaboration was able to study the only three known specimens of Tembeassu marauna, held at the University of São Paulo’s Zoology Museum. The results enabled scientists to classify the species more precisely.
An analytical tool available online assessed data from over 1 million walking and cycling trips in Boston (USA) with the aim of strengthening public strategies for the encouragement of non-motorized forms of urban mobility.
A collaboration involving researchers in Brazil and France studied the origins of the unique shape of this cluster of stars, gas and dust. Their findings showed that the nebula is part of a shell structure produced by three supernova explosions.
The technique can contribute to a deeper understanding of neurodegenerative diseases and lead to applications in drug testing. In the future, this technique could be used to reconstruct damaged parts of the brain.
The device was developed by Brazilian scientists using nontoxic, biodegradable, low-cost materials. It can be used by people with diabetes to monitor blood sugar.
A study conducted at the National Synchrotron Light Laboratory in Campinas, Brazil, shows that it is possible to enhance the ductility of additively manufactured maraging steel, an ultrahigh strength material used in the aerospace industry.
Using advanced molecular biology techniques, researchers discover that two frog species widely distributed in Brazil may actually be as many as seven, some exclusive to the Amazon. The change in classification could require new conservation actions.
Studies of food crops such as corn, sugarcane, rice, wheat, soybeans and cocoa, as well as rubber trees, were presented at an event organized by FAPESP and the Japanese agency JST to foster collaboration between researchers from São Paulo State and Japan.
Technology developed by Brazilian startup Bioware uses the pyrolysis of eucalyptus, urban garbage and other types of biomass to make fuel for boilers and furnaces.
Facilities installed in the Amazon Rainforest in Brazil and in an English temperate forest will simulate a 50% rise in atmospheric carbon dioxide to assess the impact on ecosystems.
A Brazilian research group tested the effects of different chemical groups added to the surface of nanoparticles with the aim of making them ‘invisible’ to the immune system, safe for human cells, and effective against pathogens and tumors.
Researchers describe two pre-programmed strategies used by the human organism to combat infection: resistance to pathogens by means of fever; and temporary tolerance promoted by controlled hypothermia. A combination of these two mechanisms could afford an alternative approach to studying and treating severe conditions such as sepsis.
Compounds based on palladium, a metal belonging to the same group as platinum, have been developed by researchers from Brazil, the UK and Italy. In vitro tests show action against tumor cells that are resistant to treatment currently used in clinical practice.
Brazilian startup develops software to optimize the budgets of small and medium cities. The project was selected in a call for proposals issued by FAPESP to support innovation in public administration.
Researchers at Paris Diderot University in France propose the use of vesicles secreted by adipose stem cells as a biological therapeutic system. The methodology has been successfully tested in pigs.
Agreement between São Paulo State University and American Chemical Society facilitates the compilation of information dispersed across more than 30,000 scientific articles.
Research led by a Brazilian scientist facilitates the analysis of materials comprising a large number of three-dimensionally structured atoms, such as barium molybdate, with potential applications in luminescence and organic compound degradation.
Experiments performed by Brazilian scientists showed that Zika virus inhibits tumor cell proliferation even when inactivated by high temperature. The study was supported by FAPESP and published in Scientific Reports.
Partnering with scientists at Harvard, a group of Brazilians affiliated with the Center for Research on Inflammatory Diseases (CRID), supported by FAPESP, described the mechanisms that cause hair color loss in extreme situations.
Brazilian researchers used a computer simulation to investigate the phenomenon. The study, published in Scientific Reports, could have technological applications in the future.