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In defense cells from patients hospitalized with the disease, Brazilian researchers found signs of activation of a protein complex called the inflammasome, responsible for initiating the inflammatory response that can damage organs and lead to death. The findings could help identify drugs capable of interrupting the process.

An article in Science Advances shows high school students are steadily becoming more sensitive to environmental and scientific ideas. However, interest is uneven in regional terms. It is most intense in the North, less so in the Southeast.

Study shows that a tree frog endemic to a mountainous region of the Brazilian savanna is unable to disperse and find genetically closer mates when the terrain is rugged, potentially endangering survival of the species. The findings show that topography is an important factor for conservation policy.

Researchers at the University of São Paulo identified proteins found at augmented levels in the blood plasma of high-risk patients using equipment present in Brazilian hospitals. The result of the test could help physicians make better-targeted decisions.

In an online seminar organized by FAPESP, social scientists and behavior analysts discussed the psychological, political and cultural factors that influence the way different countries and groups respond to the pandemic.

Study by FAPESP-Shell Engineering Research Center hosted at University of Campinas set out to develop supercapacitors that store more energy and batteries that charge faster.

With FAPESP’s support, the Nuclear and Energy Research Institute is assembling a world-class laboratory that associates nanotechnology with radiopharmacy. The aim is to develop new products, mainly for cancer treatment.

Research shows how Nef subverts human cells’ defense mechanisms to enable HIV to advance; Brazilian scientists comment on progress in this area in Nature group journal article.

A cross-border team of researchers refute arguments that carbon debt, opportunity cost and indirect land-use change prevent greenhouse gas mitigation by biofuels.

Scientists at a research center supported by FAPESP identified a non-inherited mutation in blood cells from a patient with GATA2 deficiency that may have prevented bone marrow failure and other clinical manifestations.

Preliminary results of patient tissue analysis show that the virus infects adipocytes and alters the quantity of signaling molecules released by these cells into the bloodstream.

In laboratory tests, the material eliminated 79.9% of SARS-CoV-2 particles in three minutes and 99.99% in up to 15 minutes.

Analysis of DNA from 1,171 over-sixties living in São Paulo will enable scientists to identify genetic mutations responsible for diseases or important to healthy aging, according to the authors of the study.

Group led by Brazilian ecologist shows defaunation wiped out 40% of the ecosystem services provided or supported by mammals, such as ecotourism, disease control and soil formation. Large-bodied mammals are disappearing fastest.

Potential applications of research conducted at the University of São Paulo include high-precision metrology and information encoding.

Researchers examine retinas and find high prevalence of type 2 diabetes as well as ocular problems caused by the disease.

Model developed by startup supported by FAPESP enables scientists to assess efficacy and safety of sunscreens and anti-aging products under conditions closely resembling real life.

Incentives to drive a rapid recovery by the sector, one of the hardest hit by the COVID-19 pandemic, will contribute to a resumption of world economic growth, save or create millions of jobs, and contain global emissions of carbon dioxide, experts say.

Monoclonal antibody tested by researchers at University of São Paulo and experimental drug given to patients in Italy by University of Pennsylvania research group promoted rapid improvement of respiratory function in patients hospitalized in severe condition.

Investigation conducted by international group of researchers showed that chikungunya virus can cause neurological infections. Risk of death in subacute phase is higher for patients with diabetes and significant for young adults.

Three waves of the disease swept the state between 2016 and 2018. An international group of researchers described how the virus spread in a study published in PLOS Pathogens based on the sequencing of 51 viral isolates extracted from mosquitoes and monkeys.

Intervention was tested in mice by Brazilian researchers. Study showed that targeted stimulation of PKA production promoted muscle growth and enhanced resistance to fatigue.

Devices developed by Brazilian startup BioLambda decontaminate face shields, surfaces, workspaces and air.

Sirius’s protein crystallography beamline analyzed more than 200 protein crystals from the novel coronavirus as they were exposed to tiny fragments of widely used drugs. If a compound fits perfectly into a target protein, its action can be blocked in the virus.

Brazilian researchers discovered that sTREM-1 protein in immunoglobulin family could be a very useful biomarker to help medical teams make clinical decisions.

Findings reported by Brazilian researchers in PLOS Neglected Tropical Diseases help explain why only some babies whose mothers are infected during pregnancy are born with microcephaly and other anomalies.

Adaptation of muscle tissue to aerobic exercise alters the metabolism of muscle stem cells, helping them recover from injury. Findings may contribute to treatment of cachexia, sarcopenia and other conditions associated with lean mass loss.

Renowned scientists will address topics related to how society has been coping with this threatening environment and will discuss factors that influence behavioral change.

Analysis identified 525 genes encoding proteins that act on the nervous system, cardiovascular system and cell walls. One of the molecules proved effective against cancer cells in preliminary test results.

The newest Engineering Research Center will initially focus on challenges relating to health, the environment, food production chains, the future of work, and the development of natural language processing tools for Brazilian Portuguese.