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With support from FAPESP via its program to fund innovative research, the startup has developed a rejuvenating serum based on bioactives obtained from sweet wormwood, a plant used in traditional Chinese medicine.

A research group at São Paulo State University (UNESP) analyzed how Candida albicans fungi and Staphylococcus aureus bacteria influence gene expression and tumor cell survival.

The call aims to advance knowledge of the societal effects of the COVID-19 pandemic and solutions to mitigate them. The submission deadline is July 12. Eligibility checking ends June 14.

Brazilian researchers studied the case of identical twins in which only one sibling was reinfected and developed complications after a second exposure to the virus. Their analysis showed that the adaptive immune response can be different even between individuals with the same genome.

Workers with blood lead levels below the legal ceiling in Brazil expressed a microRNA associated with a decrease in DNA methylation, a physiological process required for the organism to be in balance. However, known clinical manifestations occur when levels are high.

The study showed that interdisciplinary action facilitates weight loss, improves quality of life and eating behavior, and reduces symptoms of depression.

A call for proposals issued jointly with the Ministry of Science, Technology and Innovation and the Brazilian Internet Steering Committee selected the new research centers, which will focus on health, agriculture, manufacturing, and smart cities.

Strategies to increase funding for action-oriented research that helps make societies and economies more resilient, equitable and sustainable were the focus for the Second Global Forum of Funders, held online on April 26-28.

Trials performed by researchers at the University of São Paulo with healthy young adults show that the right level of protein intake is the key to muscle health, regardless of protein source.

This is the main finding of a study published in Clinical Infectious Diseases. The authors analyzed blood samples collected in a town in the Brazilian Amazon before and after the first wave of the pandemic to detect the presence of antibodies against dengue virus and SARS-CoV-2.

Brazilian scientists conducted preclinical trials to test membranes produced from mesenchymal stem cells that can differentiate to cartilage and promote local immunoregulation.

Whole mitochondrial DNA sequencing of the three extant species of the aquatic mammal shows that they first split from their common ancestor after geological events isolated the South American region from the sea. The African species may have originated in migration borne by marine currents.

A review article by Brazilian researchers shows that alterations in the defense cell metabolism may explain why many patients who survive sepsis die within a year or suffer from long-term complications

Conclusion was drawn from a study that involved 92 adolescents aged 11-18. The findings underscore the importance of considering differences between the sexes when treatment is planned.

A study by scientists at a FAPESP-supported research center analyzed genetic material from 86 couples in which only one spouse was infected. The results suggest that more frequent variants in the resistant spouses could lead to more efficient activation of natural killer (NK) cells, which are part of the innate immune system, the first barrier against infection.

The research group created a virus capable of acting on specific adult brain regions, helping to elucidate the role of key neurons in the prefrontal cortex. They tested the technique on mice.

In an article published in PLOS ONE, scientists at a FAPESP-supported research center describe the impact of hypoproteinemia on the expression of microRNAs associated with kidney development in rat embryos.

Brazilian researchers show that feed supplementation improves fatty acid profile of milk and promotes a healthier omega-6/omega-3 ratio.

A mutation in the variant’s spike protein is associated with glycosylation, which prevents antibodies from binding strongly to the virus. If the discovery is confirmed by further research, it could serve as a basis for future vaccines that are more effective against novel variants.

According to researchers affiliated with the University of São Paulo, these indicators can orient preventive care for the most vulnerable and rehabilitation for survivors who suffer from long-term complications.

Researchers at the University of Campinas in Brazil reveal the mechanisms whereby SARS-CoV-2 disrupts the regulation of inflammation, coagulation and blood pressure when it infects alveolar cells, responsible for gas exchange in the lungs.

Researchers analyzed the effects of wildfires on plant cover and soil quality in the last 40 years. The findings of the study show that the forest is highly vulnerable even in well-conserved areas far from the ‘deforestation arc’.

People with diseases such as rheumatoid arthritis and lupus are more likely to have heart attacks, angina, and strokes. A review of the scientific literature on the subject shows that regular exercise improves vascular function in these patients.

Inexpensive test is non-invasive and based on detection of bladder cancer biomarkers in urine.

Sample collection is much easier and less invasive. Self-collecting is feasible, depending on the child’s age. Schools should reopen only with mass testing to keep track of asymptomatic cases, the researchers argue.

A multinational research group used data from São Paulo to perform calculations which suggest that even a minor reduction in the city’s mobility – equivalent to a rise from 45% to 50% in the social distancing index – correlates with a considerable fall in new infections and deaths after a few days.

A simple and affordable solution developed by researchers at the University of São Paulo and a Nigerian collaborator eliminates even multi-resistant bacteria. Clay, papaya seeds and banana peel are among the raw materials used by the group.

Butterflies are considered a key biological indicator of trends in the biome. The study quantified the contributions of landscape and climate variables to current species distribution patterns.

Resonant-tunneling diodes are used in high-frequency oscillators, wave emitters and detectors, logic gates, photodetectors, and optoelectronic circuits. The study was a collaboration between Brazilian and German researchers.

A clinical trial was conducted by researchers at the University of São Paulo with 240 patients who were given 200,000 IU of vitamin D3 on admission to hospital. The supplementation did not reduce length of stay or affect the proportion requiring intensive care.