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Research reveals the mechanisms whereby methionine-deficient and methionine-supplemented diets can alter gene expression and damage liver cells.

The workshop was a side event to the Annual Meeting of the Global Research Council. The need to dialogue with and learn from traditional communities, especially Indigenous peoples, was emphasized in the discussions.

The approach combined nanotechnology, chemotherapy and monoclonal antibodies. It produced promising in vitro and in vivo results against glioblastoma multiforme.

Analysis of blood samples showed that sharks living near urban areas have a lower-quality diet than those living in wilderness areas. Dietary imbalances can impair important physiological processes, such as cardiovascular tone, inflammatory response and reproduction.

The GRC is an association of more than 60 public research funding agencies on all continents. Its annual meeting took place in Panama on May 31-June 03, 2022.

Formed in high-energy collisions such as those produced by the LHC at CERN, quark-gluon plasma lasts only a fraction of a second. Its decay gives rise to a cascade of particles displaying self-similarity over many scales that is typical of fractals.

Monitoring since 2011 shows that emission levels vary significantly from one part of the complex to another, making the standards used in environmental impact assessments and the carbon credit market unreliable.

Universities, research institutions and agencies of the São Paulo State Government will join forces in 15 new centers announced during a ceremony held to celebrate FAPESP’s 60th anniversary. The centers will address problems in areas ranging from human and animal health to the energy transition and climate change.

The results of a clinical trial are reported by Brazilian researchers in Frontiers in Cardiovascular Medicine. According to the authors, if corroborated by more robust research, the findings indicate that the method can be used in emergency treatment of hypertensive crisis patients.

The material, created by startup Protech, can be used in face masks and surgical gowns. Other applications identified by the firm’s founder during the training course offered by the FAPESP Innovative Research in Small Business Program (PIPE) include air conditioning filters, diapers and tampons.

A startup supported by FAPESP has developed a face cream and body lotion based on cocoa juice, which is usually thrown away. The entrepreneur has been selected for the 2022 Leaders in Innovation Fellowships training program in the UK.

School will take place in September at the University of São Paulo in Ribeirão Preto focusing on leishmaniasis and Chagas disease. Graduate students and postdocs may apply until June 26.

The open-access platform developed by researchers at the University of São Paulo offers access to strategic information on microorganisms classified by WHO as a “critical priority”. The aim is to contribute to the monitoring and control of bacteria that pose a great threat to human and animal health.

Officially launched on May 18, BIOTA Synthesis is one of FAPESP’s new Science for Development Centers. In the next five years it will develop solutions to challenges relating to sustainable agriculture, water security and control of zoonotic diseases.

Mathematic simulations showed that well-executed non-pharmacological measures reduce the spread of COVID-19 even in places with low vaccination coverage. According to the authors, however, up to 80% of the population could catch the disease if preventive protocols are abandoned.

Projects will focus on future aerial mobility, digital networks and services, and immuno-oncology.

In tests conducted at the University of São Paulo, microparticles produced from the unripe fruit performed similarly to TBHQ, a synthetic compound present in processed foods and in cosmetics. The findings are reported in Future Foods.

Experiments involving isolated and cultured cells as well as animals and babies suggest that short-chain fatty acid acetate produced in the gut can minimize the effects of infection by respiratory syncytial virus.

Brazilian researchers demonstrated this finding in experiments with broiler chicks. Regulated hypothermia, a strategy of the immune system also observed in mammals, is a way to avoid the high energy expenditure entailed by maintaining a fever under unfavorable conditions.

The new species of beetle in the family Buprestidae was found in the state of Bahia and described by researchers at the University of São Paulo and collaborators. The group discovered how the insect contributes to production of red propolis by honey bees.

With aging, mutant genetic material tends to build up in the organelles responsible for producing energy, and this can lead to disease. Brazilian researchers have discovered that a cell cleansing mechanism known as autophagy can modulate this phenomenon.

Three new Engineering Research Centers, 15 new Science for Development Centers, and calls for proposals to fund research infrastructure, among others, will entail investment of BRL 990 million.

The hypothesis is raised by researchers at São Paulo State University and collaborators in the journal Icarus. Rich in ammonia and water ice, Ceres is a survivor of the initial stage of the Solar System’s formation and could contain primitive life forms.

An article in Scientific Reports shows that experimental treatment with a protein-derived molecule reduced tumor growth and metastasis, increasing the survival of mice by 25%.

An online meeting was held to present recent changes to the FAPESP Innovative Research in Small Business Program (PIPE) and highlight the attractiveness of the startups it supports to players in the innovation ecosystem.

Researchers at the University of São Paulo are acquiring a deeper understanding of witch’s broom disease, which all but destroyed Brazil’s cocoa industry in the late twentieth century. Their discovery of the pathogen’s action mechanism could provide clues as to how to combat the disease efficiently.

Devices that combine laser irradiation, ultrasound and suction help regenerate tissue and treat muscle, joint, skin, neurological and lung damage. Protocols created via business-university partnerships are being tested and can be applied by treatment centers across Brazil.

El Niño-driven extreme drought and forest fires in 2015-16 caused the loss of 3 billion trees and emissions of 495 million metric tons of carbon dioxide in the ensuing three years, destroying more than deforestation throughout the Brazilian Amazon.

Researchers affiliated with the University of São Paulo’s Medical School compared immune cells from COPD patients, healthy young and old adults, and smokers. The finding helps explain why these patients respond poorly to vaccines and are more susceptible to infections.

Startup supported by FAPESP has developed a novel material based on an innovative strategy that uses cellulose fibers to reassemble graphite crystals.