The platform was developed by a startup supported by FAPESP. It uses an adult learning methodology that leverages motivational techniques and customization.
Results of trials involving animals, cell cultures and human heart tissue are reported in the European Heart Journal. The study was conducted by researchers at USP in partnership with a biopharmaceutical firm, offering hope to 2 million Brazilians who suffer from the disease.
An article published in PNAS by Brazilian and Australian researchers describes a hitherto unknown protein with anti-oxidizing properties secreted by Coxiella burnetii, a Gram-negative intracellular bacterium, pointing to possible treatments for auto-immune diseases and even cancer.
This was a consensus among representatives of funding agencies in the Americas who met virtually in October under the aegis of the Global Research Council. A previous event discussed funding for research relating to artificial intelligence in Latin America.
Highlighted on the cover of the journal Biochemistry, a study by Brazilian researchers shows that a chemical change called pyroglutamination can occur spontaneously during peptide synthesis. The discovery has implications for laboratory experiments and research on Alzheimer’s, Parkinson’s and other diseases associated with the formation of amyloid aggregates.
The test developed by Brazilian researchers accurately identifies the causative agent in less than two hours, so that treatment can be properly targeted. Brazil is seeing a growing number of cases of co-infection by protozoans Leishmania infantum and Crithidia.
High-precision maneuvering support system with integrated hardware and software developed by a startup supported by FAPESP transmits dynamic information in real-time via a smart platform.
A study compared geographical and socioeconomic dimensions of the disease in São Paulo and the Barretos region. Incidence was far higher in the former but mortality rates were similar, suggesting overdiagnosis in specific areas and social groups.
Researchers at the Federal University of São Paulo analyzed allegedly biodegradable plastic items sold by 40 supermarkets and found most to be oxo-degradables, banned in several countries because they contribute significantly to microplastic pollution. Bills currently before Brazil’s Congress would regulate the sale of such products.
A study conducted in sustainable-use reserves shows that local game species become less abundant about 5 kilometers away from the nearest human community, but the negative effects of anthropic activity can be mitigated by appropriate management strategies.
In nematode worms exposed to a compound secreted by pathogenic bacteria, researchers observed activation of a neural circuit resulting in a longer lifespan and less protein aggregation, one of the causes of neurodegenerative diseases. The discovery paves the way for the development of treatments for age-related diseases.
Brazilian researchers showed that brain activity of Ndel1, an enzyme that plays an important role in neuron differentiation and migration, decreased in mice infected by zika during pregnancy. The enzyme could become a biomarker for early diagnosis of the congenital syndrome associated with zika.
The product, which contains the anti-inflammatory protein annexin A1, accelerated complete skin wound healing in mice, and has the potential to become part of the arsenal of treatments for a disease that affects 17.7 million Brazilians.
Opened in 2022 with FAPESP’s support, Nutera is Latin America’s first cellular product manufacturing plant. It is run by researchers from Butantan Institute and the University of São Paulo’s Ribeirão Preto Blood Center, and could become a supplier to the SUS, Brazil’s public healthcare network.
This is one of the findings of a study led by Brazilian scientists and reported in the science journal Fire. The researchers built a model based on images from the SENTINEL-2 satellite and were able to detect burned areas much more accurately.
Findings reported in the journal Antibiotics by scientists working in Brazil and the United States pave the way for the development of drugs against resistant bacteria.
Plant species native to the Brazilian savanna-like biome grow thick bark to protect their internal tissues and hide organs that assure resprouting below the ground, according to an article in Flora by researchers at São Paulo State University.
The calls offer opportunities for accelerators and agencies that provide services for startups under the aegis of Tecnova III, a program run by the Brazilian Innovation Agency which in São Paulo is operationalized in partnership with FAPESP.
In addition to helping combat antimicrobial resistance, the bioparticle developed at the Federal University of São Paulo avoids the waste and pollution created by excessive amounts of drugs in water bodies. The strategy was tested on an ornamental fish species native to the Amazon and found to be safe.
Record levels of destruction of native vegetation in the Brazilian savanna, the second-largest biome in South America, motivated the letter published in Nature Sustainability. The scientists who wrote it stress the need for specific measures to conserve the Cerrado’s rich biodiversity.
Dutch-born scientist Martinus Theodorus van Genuchten is the author of a famous equation describing the hydraulic conductivity of unsaturated soil. His discoveries are central to agricultural operations and climate science, and he recently won the prestigious Wolf Prize in Agriculture.
Research conducted at the University of São Paulo involving 95 volunteers associated poor sleep quality with a deterioration in the complications caused by aging and overweight, such as anxiety, depression, body fat gain, and loss of muscle mass and strength.
According to experts interviewed by Agência FAPESP, classic indicators based on numbers of articles and citations are being replaced by a multidimensional approach that encompasses teaching, research, extension, culture and outreach.